US2008188643A1PendingUtilityA1

flk-1 binding protein

Assignee: IMMUNEX CORPPriority: Nov 8, 1995Filed: Dec 13, 2007Published: Aug 7, 2008
Est. expiryNov 8, 2015(expired)· nominal 20-yr term from priority
C07K 14/47A61K 38/00C07K 14/715
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Claims

Abstract

A protein designated flk-1bp binds the vascular endothelial cell surface receptor flk-1. Isolated DNA encoding flk-1bp is provided, along with expression vectors and transformed host cells useful in producing flk-1bp polypeptides. Antibodies that are immunoreactive with flk-1bp are generated using the polypeptides disclosed herein.

Claims

exact text as granted — not AI-modified
1 . An antibody or antibody fragment which specifically binds a flk-1 binding protein polypeptide, wherein the flk-1 binding protein polypeptide consists of the amino acid sequence of residues-20 to 399 of SEQ ID NO:1 or residues 1 to 399 of SEQ ID NO:1. 
     
     
         2 . The antibody of  claim 1 , wherein the antibody is a monoclonal antibody. 
     
     
         3 . The antibody fragment of  claim 1 , wherein the fragment is selected from the group consisting of Fab, F(ab′), and F(ab′) 2 .

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