US2008145337A1PendingUtilityA1

Method and pharmaceutical composition for treating inflammation

68
Assignee: YEDA RES & DEVPriority: Sep 17, 2001Filed: Feb 19, 2008Published: Jun 19, 2008
Est. expirySep 17, 2021(expired)· nominal 20-yr term from priority
Inventors:Idit ShacharLiat Flaishon
A61K 38/217A61P 29/00Y02A50/30
68
PatentIndex Score
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Cited by
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References
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Claims

Abstract

A method of treating an inflammation in a subject in need thereof is disclosed. The method comprises locally or systemically administering to the subject IFN-gamma in an amount so as to achieve an IFN-gamma bulk tissue concentration at a site of inflammation of 1-8,000 units per kilogram body weight, thereby ameliorating the inflammation.

Claims

exact text as granted — not AI-modified
1 . A pharmaceutical composition for treating an inflammation in a subject in need thereof, each dose-unit of the pharmaceutical composition comprising, as an active ingredient, IFN-γ in an amount of 0.0001-3,600 units. 
     
     
         2 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-360 units. 
     
     
         3 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-36 units. 
     
     
         4 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-12.6 units. 
     
     
         5 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-11.7 units. 
     
     
         6 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-10.8 units. 
     
     
         7 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-9.9 units. 
     
     
         8 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001-9 units. 
     
     
         9 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0001 unit. 
     
     
         10 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0002-8 units. 
     
     
         11 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.0005-8 units. 
     
     
         12 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.001-8 units. 
     
     
         13 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.002-8 units. 
     
     
         14 . The pharmaceutical composition of  claim 1 , wherein said amount is of 0.004-8 units. 
     
     
         15 . The pharmaceutical composition of  claim 1 , wherein said pharmaceutical composition comprises a pharmaceutically acceptable carrier adapted for systemic administration. 
     
     
         16 . A pharmaceutical composition for treating an inflammation in a subject in need thereof, the pharmaceutical composition comprising, as an active ingredient, IFN-γ in an amount of 0.0001-50 units, and a pharmaceutically acceptable carrier. 
     
     
         17 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.00014 unit. 
     
     
         18 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.0001-0.4 unit. 
     
     
         19 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.0002-8 units. 
     
     
         20 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.0005-8 units. 
     
     
         21 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.001-8 units. 
     
     
         22 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.002-8 units. 
     
     
         23 . The pharmaceutical composition of  claim 16 , wherein said amount is of 0.004-8 units. 
     
     
         24 . The pharmaceutical composition of  claim 16 , wherein said pharmaceutical carrier is adapted for local administration.

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