Therapy for obsessive compulsive head banging

Abstract

Methods for treating a head banging disorder by local administration of a Clostridial toxin. The local administration can be by intramuscular, transdermal, intradermal or subdermal administration of a low dose of botulinum toxin.

1 . A method for treating a head banging disorder, the method comprising a step of local administration of a botulinum toxin to a patient with a head banging disorder, thereby treating the head banging disorder.  
     
     
         2 . The method of  claim 1 , wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E, F and G.  
     
     
         3 . The method of  claim 1 , wherein the botulinum toxin is botulinum toxin type A.  
     
     
         4 . The method of  claim 1 , wherein the botulinum toxin is administered in an amount of between about 1 unit and about 1,500 units.  
     
     
         5 . The method of  claim 1 , wherein the treating persists for between about 1 month and about 5 years.  
     
     
         6 . The method of  claim 1 , wherein the local administration of the botulinum toxin is to a head muscle.  
     
     
         7 . The method of  claim 1 , wherein the local administration of the botulinum toxin is to a facial muscle.  
     
     
         8 . The method of  claim 1 , wherein the local administration is by intramuscular injection.  
     
     
         9 . The method of  claim 1 , wherein the local administration of the botulinum toxin is to a dermal location or to a muscle location from which the patient perceives the existence of a premonitory sensation, which leads to the generation of the head banging disorder, to arise.  
     
     
         10 . A method for treating a head banging disorder in a patient in need thereof, the method comprising a step of local administration of a botulinum toxin to forehead muscles the patient, thereby treating the head banging disorder.  
     
     
         11 . The method of  claim 10 , wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E and G.  
     
     
         12 . The method of  claim 10 , wherein the botulinum toxin is botulinum toxin type A.  
     
     
         13 . The method of  claim 10 , wherein the botulinum toxin is administered in administered in an amount of between about 1 unit and about 1500 units.  
     
     
         14 . The method of  claim 10 , wherein the head banging disorder is treated for between about 1 month to about 5 years.  
     
     
         15 . A method for treating a head banging disorder in a patient in need thereof, the method comprising a step of local administration of at least one botulinum toxin selected from the group consisting of botulinum toxin type A, B, C, D, E, F and G, to a forehead muscle of the patient, thereby treating the head banging disorder.  
     
     
         16 . The method of  claim 15 , wherein the local administration is by intramuscular injection.  
     
     
         17 . The method of  claim 16 , wherein the botulinum toxin is type A and is administered at doses of between about 1 unit and about 125 units per injection site.  
     
     
         18 . The method of  claim 16 , wherein the botulinum toxin is type B and is administered at doses of between about 40 units and about 1500 units per injection site.