Cardiovascular compositions and methods using combinations of anti-platelet agents

Abstract

A method and composition for inhibiting a variety of pain, inflammation, spasm and restenosis processes resulting from cardiovascular or general vascular therapeutic and diagnostic procedures. The composition preferably includes multiple pain and inflammation inhibitory agents and spasm inhibitory agents. Specific preferred embodiments of the solution of the present invention for use in cardiovascular and general vascular procedures also may include anti-restenosis agents.

1 . A cardiovascular therapeutic composition consisting essentially of an ADP receptor antagonist and a thromboxane A 2  receptor antagonist. 
     
     
         2 . A pharmaceutical combination consisting essentially of an ADP receptor blocking antiplatelet drug and a thromboxane A 2  receptor antagonist. 
     
     
         3 . The composition of  claim 2 , wherein the ADP receptor blocking antiplatelet drug comprises clopidogrel. 
     
     
         4 . A method for preventing or inhibiting platelet aggregation in a mammalian species, which comprises administering to a patient in need of treatment a therapeutically effective amount of a pharmaceutical combination as defined in  claim 3 .