US2008076725A1PendingUtilityA1

Clathrate of Azithromycin Hydrate With 1,2-Propyleneglycol, Method For The Manufacture Thereof, And Pharmaceutical Composition containing same

Assignee: SUH KWEE-HYUNPriority: Apr 25, 2001Filed: Mar 2, 2007Published: Mar 27, 2008

Est. expiryApr 25, 2021(expired)· nominal 20-yr term from priority

Inventors:Kwee Hyun Suh Gi Jeong Kim Sang Min Yoon Mi-Ra Seong Gwan Sun Lee

A61P 31/04A61K 31/7028A61P 31/00C07D 413/14

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Claims

Abstract

The present invention relates to a clathrate of azithromycin hydrate with 1,2-propyleneglycol of formula (I), a method for the manufacture thereof, and a pharmaceutical composition containing same. The inventive compound is much less hygroscopic than azithromycin hydrate or crystals known in the art, therefore, it can be useful for the preparation of a medicine for treating various microbial infections. wherein m ranges from 1 to 2 and n, from 0.30 to 0.45.

Claims

exact text as granted — not AI-modified

1 - 7 . (canceled)  
     
     
         8 . A non-aqueous pharmaceutical composition for treating bacterial infection, comprising a clathrate compound of azithromycin hydrate with 1,2-propyleneglycol of formula (I) and a pharmaceutically acceptable carrier:

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