Pharmaceutical compositions

Abstract

The present invention relates to an improved mode of administration for cannabis and its natural and synthetic derivatives. A pharmaceutical composition suitable for sublingual aerosol or spray delivery of cannabis is provided. The formulation may be dispensed using a pump spray or the formulation may include a propellant, such as butane, 1,1,1,2-tetrafluoroethane (HFC-134a) or 1,1,1,2,3,3,3-heptafluoropropane (HFC-227). The term cannabis is used herein to refer to all physiologically active substances derived from the cannabis family of plants and synthetic cannabis analogues and derivatives, precursors, metabolites etc., or related substances having cannabis-like physiological effects.

1 . A pump spray device comprising a pharmaceutically active agent which is cannabis, wherein the cannabis is a liquid extract derived from the cannabis plant.  
   
   
       2 . A pump spray device as claimed in  claim 1 , further comprising at least one carrier.  
   
   
       3 . A pump spray device as claimed in  claim 2 , wherein the at least one carrier is ethanol.  
   
   
       4 . A pump spray device as claimed in  claim 2 , wherein the at least one carrier is propylene glycol.  
   
   
       5 . A pump spray device as claimed in  claim 2 , wherein the composition comprises a plurality of carriers.  
   
   
       6 . A pump spray device as claimed in  claim 5  wherein the plurality of carriers comprise ethanol and propylene glycol.  
   
   
       7 . A pump spray device as claimed in  claim 1 , further comprising a flavoring oil.