Apparatus for Treatment of Dermatological Conditions

Abstract

This invention relates to ultrasound delivery apparatus comprising flexible arrays of transducers and to methods and topical compositions for the treatment of skin, in particular for the treatment of cosmetic skin conditions and to improve the appearance of sun damaged and/or aged skin; the invention further relates to the use of such apparatus and compositions in methods of treating skin, which methods may incorporate the application of ultrasound. The composition may comprise one or more anti-gfycation agent, one or more anti-oxidant, a dermatologically acceptable excipient and optionally one or more substance capable of inducing expression of a molecular chaperone.

1 - 74 . (canceled)  
   
   
       75 . An apparatus for application of ultrasound to the skin comprising a plurality of ultrasound transducer elements arranged as an array in a flexible material in spaced configuration, wherein the ultrasound transducer elements are capable of delivering ultrasound at low and/or high frequency to an area of the skin.  
   
   
       76 . An apparatus according to  claim 75 , wherein the ultrasound transducer elements are capable of delivering low and high frequency ultrasound simultaneously or sequentially.  
   
   
       77 . An apparatus according to  claim 75 , wherein the transducer elements are dual frequency transducer elements capable of delivering low and high frequency ultrasound sequentially or simultaneously.  
   
   
       78 . An apparatus according to  claim 77 , wherein the dual frequency transducer elements are capable of delivering low and high frequency ultrasound along a common axis.  
   
   
       79 . A dual frequency transducer element comprising a high frequency transducer element and a low frequency transducer element.  
   
   
       80 . A composition comprising one or more anti-glycation agent, one or more anti-oxidant, a dermatologically acceptable excipient and optionally one or more substance capable of inducing expression of a molecular chaperone.  
   
   
       81 . A method for treatment of the skin, comprising applying to the skin a composition according to  claim 80 .  
   
   
       82 . The use of a composition according to  claim 80  in the manufacture of a composition for the treatment of a skin condition.  
   
   
       83 . A dressing comprising a composition according to  claim 80 .  
   
   
       84 . A kit comprising a composition according to  claim 80  and a device comprising an ultrasound source and/or an applicator for applying ultrasound to the skin and/or for applying the composition to the skin.