Cholesterol regulating agent

Abstract

It is an object of the present invention to provide a HDL cholesterol-raising agent which can selectively raise or maintain HDL cholesterol level, an LDL cholesterol-lowering agent which can selectively lower LDL cholesterol level, a composition which can selectively raise of maintain HDL cholesterol level, a method for raising or maintaining HDL cholesterol level in blood and a method which can raise or maintain HDL cholesterol level and lower LDL cholesterol level in blood. Therefore, provided are a HDL cholesterol-raising agent and LDL cholesterol-lowering agent containing an olive extract as an active ingredient, a composition containing the HDL cholesterol-raising agent, and a method for raising HDL cholesterol level and a method for raising HDL cholesterol level and lowering LDL cholesterol level in which olive extracts are administered to mammals.

1 - 10 . (canceled)  
   
   
       11 . A method for raising HDL cholesterol level in blood, comprising: 
 administration of an olive extract to mammals.    
   
   
       12 . The method for raising HDL cholesterol level in blood according to  claim 11 , wherein the olive extract comprises Oleuropein.  
   
   
       13 . A method for raising HDL cholesterol level and lowering LDL cholesterol level in blood, comprising: 
 administration of an olive extract to mammals.    
   
   
       14 . The method for raising HDL cholesterol level and lowering LDL cholesterol level in blood according to  claim 13 , wherein the olive extract comprises Oleuropein.  
   
   
       15 . A method for modifying the level of cholesterol in a mammal, said method comprising: 
 (a) administering an olive extract to the mammal; wherein the level of cholesterol in the mammal is modified in at least one manner selected from the group consisting of raising the HDL cholesterol level, lowering the LDL cholesterol level and combinations of the foregoing.    
   
   
       16 . A method according to  claim 15 , wherein the olive extract comprises oleuropein.  
   
   
       17 . A method according to  claim 15 , wherein the manner comprises lowering the LDL cholesterol level.  
   
   
       18 . A method according to  claim 15 , wherein the manner comprises raising the HDL cholesterol level.  
   
   
       19 . A method according to  claim 16 , wherein the manner comprises lowering the LDL cholesterol level.  
   
   
       20 . A method according to  claim 16 , wherein the manner comprises raising the HDL cholesterol level.  
   
   
       21 . A method for modifying the level of cholesterol in a mammal, said method comprising: 
 (a) administering an olive leaf extract to the mammal;    wherein the level of cholesterol in the mammal is modified in at least one manner selected from the group consisting of raising the HDL cholesterol level, lowering the LDL cholesterol level and combinations of the foregoing.    
   
   
       22 . A method according to  claim 21 , wherein the olive leaf extract comprises oleuropein.  
   
   
       23 . A method according to  claim 21 , wherein the manner comprises lowering the LDL cholesterol level.  
   
   
       24 . A method according to  claim 21 , wherein the manner comprises raising the HDL cholesterol level.  
   
   
       25 . A method according to  claim 22 , wherein the manner comprises lowering the LDL cholesterol level.  
   
   
       26 . A method according to  claim 22 , wherein the manner comprises raising the HDL cholesterol level.