Method and composition for treating ear inflammation caused by dry ear

Abstract

A method of treating diseases and conditions associated with dry ear comprising topically applying to the ear canal of a subject that is suffering therefrom a liquid composition comprising an anti-irritant agent, a wound healing agent; and an anti-inflammatory agent dissolved in a polyhydroxy liquid solvent.

1 . A method of treating diseases and conditions associated with dry ear or asteatosis which comprises topically applying to the ear canal of a subject that is suffering therefrom a liquid composition comprising: 
 (a) an anti-irritant agent;    (b) a wound healing agent; and    (c) an anti-inflammatory agent: 
 dissolved in a polyhydroxy liquid solvent.  
   
     
     
         2 . The method of  claim 1  wherein said subject is a human.  
     
     
         3 . The method of  claim 1  wherein said polyhydroxy solvent is a mixture of a glycol and a glycerin.  
     
     
         4 . The method of  claim 3  wherein said polyhydroxy solvent is a mixture of butylene glycol and glycerin.  
     
     
         5 . The method of  claim 1  wherein anti-irritant is an avenanthramide.  
     
     
         6 . The method of  claim 1  wherein wound healing agent is selected from the group consisting of Aloe, alphabisolol, and a mixture thereof.  
     
     
         7 . The method of  claim 1  wherein anti-inflammatory agent is selected from the group consisting of dipotassium glycyrrhizate and White Willow Bark Extract.  
     
     
         8 . The method of  claim 1  wherein said composition further comprises a cationic surfactant.  
     
     
         9 . The method of  claim 8  wherein said composition further comprises from about 0.5 to about 10%, by weight, of said agents (a), (b), and (c).  
     
     
         10 . The method of  claim 1  wherein said liquid composition comprises from about 0.1 to about 5% of an anti-irritant agent, 0.01 to about 1% of a wound healing agent and 0.001 to about 1% of an anti-inflammatory agent.  
     
     
         11 . A composition for treating the diseases and conditions associated with dry ear which comprises; 
 (a) an anti-irritant agent;    (b) a wound healing agent; and    (c) an anti-inflammatory agent: 
 dissolved in a polyhydroxy liquid solvent.  
   
     
     
         12 . The composition of  claim 11  wherein said subject is a human.  
     
     
         13 . The composition of  claim 11  wherein said polyhydroxy solvent is a mixture of a glycol and a glycerin.  
     
     
         14 . The composition of  claim 13  wherein said polyhydroxy solvent is a mixture of butylene glycol and glycerin.  
     
     
         15 . The composition of  claim 11  wherein anti-irritant is an avenanthramide.  
     
     
         16 . The composition of  claim 11  wherein wound healing agent is selected from the group consisting of Aloe, alphabisolol and a mixture thereof.  
     
     
         17 . The composition of  claim 11  wherein anti-inflammatory agent is selected from the group consisting of dipotassium glycyrrhizate and White Willow Bark Extract.  
     
     
         18 . The composition of  claim 11  wherein said composition further comprises a cationic surfactant.  
     
     
         19 . The composition of  claim 18  wherein said composition further comprises from about 0.5 to about 10%, by weight, of said agents (a), (b), and (c).  
     
     
         20 . The composition of  claim 11  wherein said liquid composition comprises  
     
     
         21 . The method of  claim 1  wherein said liquid composition comprises from about 0.1 to about 5% of an anti-irritant agent, 0.01 to about 1% of a wound healing agent and 0.001 to about 1% of an anti-inflammatory agent.