G-GSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction

Abstract

The present invention relates to methods of using Granulocyte Colony Stimulating Factor (G-CSF) polypeptide in conjunction with reperfusion therapy in the treatment of acute myocardial infarction or other ischemic events. This treatment can be used alone or in combination with other well-known methods of treatment.

1 - 7 . (canceled)  
   
   
       8 . A kit containing components for treating myocardial infarction or occlusion in an artery comprised of: 
 a) a composition comprising G-CSF polypeptide; and    b) optionally, at least one additional factor selected from the group consisting of: EPO, SCF, M-GDF, GM-CSF, M-CSF, CSF-1, IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-1, IL-11, IL-12, IGF-1, LIF, interferon, a neurotrophic factor, a fibroblast growth factor, and human growth hormone.    
   
   
       9 - 10 . (canceled)