Anti-aging composition containing phloretin

Abstract

An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.

1 . An anti-aging composition comprising:
 (a) at least one first active ingredient chosen from phloretin and its derivatives;   (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and   (c) at least one non-aqueous organic solvent; with the proviso that, if the composition contains ascorbic acid, water is present as a co-solvent.   
   
   
       2 . The composition of  claim 1 , wherein (a) is present in the composition in an amount of from about 0.1 to about 10% by weight, based on the total weight of the composition. 
   
   
       3 . The composition of  claim 1 , wherein (a) is present in the composition in an amount of from about 1 to about 5% by weight, based on the total weight of the composition. 
   
   
       4 . The composition of  claim 1 , wherein (a) is present in the composition in an amount of from about 0.5 to about 3% by weight, based on the total weight of the composition. 
   
   
       5 . The composition of  claim 1 , wherein (a) is present in the composition in an amount of from about 1 to about 2% by weight, based on the total weight of the composition. 
   
   
       6 . The composition of  claim 1 , wherein (a) is phloretin. 
   
   
       7 . The composition of  claim 1 , wherein (b) is a cinnamic acid derivative. 
   
   
       8 . The composition of  claim 1 , wherein (b) is ferulic acid. 
   
   
       9 . The composition of  claim 1 , wherein (b) is a mixture of ferulic acid and ascorbic acid. 
   
   
       10 . The composition of  claim 8 , wherein ferulic acid is present in an amount of from about 0.2 to about 5% by weight, and ascorbic acid is present in an amount of from about 5 to about 20% by weight, all weights based on the total weight of the composition. 
   
   
       11 . The composition of  claim 1 , wherein (b) is resveratrol. 
   
   
       12 . The composition of  claim 1 , wherein (b) is present in the composition in an amount of from about 0.1 to about 20% by weight, based on the total weight of the composition. 
   
   
       13 . The composition of  claim 1 , wherein (b) is present in the composition in an amount of from about 0.2 to about 15% by weight, based on the total weight of the composition. 
   
   
       14 . The composition of  claim 1 , wherein (b) is present in the composition in an amount of from about 0.2 to about 10% by weight, based on the total weight of the composition. 
   
   
       15 . An anti-aging composition comprising:
 (a) about 2% by weight, phloretin;   (b) about 0.5% by weight, ferulic acid;   (c) about 15% by weight, ascorbic acid;   (d) about 30% by weight of a glycol; and   (e) remainder, to 100%, water.   
   
   
       16 . A process for treating radical-induced damage to skin comprising contacting the skin with a composition containing:
 (a) at least one first active ingredient chosen from phloretin and its derivatives;   (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives;   (c) at least one non-aqueous organic solvent;   
     with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent. 
   
   
       17 . The process of  claim 16 , wherein (a) is present in the composition in an amount of from about 0.1 to about 10% by weight, based on the total weight of the composition. 
   
   
       18 . The process of  claim 16 , wherein (a) is present in the composition in an amount of from about 1 to about 5% by weight, based on the total weight of the composition. 
   
   
       19 . The process of  claim 16 , wherein (a) is present in the composition in an amount of from about 0.5 to about 3% by weight, based on the total weight of the composition. 
   
   
       20 . The process of  claim 16 , wherein (a) is present in the composition in an amount of from about 1 to about 2% by weight, based on the total weight of the composition. 
   
   
       21 . The process of  claim 16 , wherein (a) is phloretin. 
   
   
       22 . The process of  claim 16 , wherein (b) is a cinnamic acid derivative. 
   
   
       23 . The process of  claim 16  wherein (b) is ferulic acid. 
   
   
       24 . The process of  claim 16 , wherein (b) is a mixture of ferulic acid and ascorbic acid. 
   
   
       25 . The process of  claim 24  wherein ferulic acid is present in the composition in an amount of from about 0.2 to about 5% by weight, and ascorbic acid is present in the composition in an amount of from about 5 to about 20% by weight, all weights based on the total weight of the composition. 
   
   
       26 . The process of  claim 16 , wherein (b) is resveratrol. 
   
   
       27 . The process of  claim 16 , wherein (b) is present in the composition in an amount of from about 0.1 to about 20% by weight, based on the total weight of the composition. 
   
   
       28 . The process of  claim 16 , wherein (b) is present in the composition in an amount of from about 0.2 to about 15% by weight, based on the total weight of the composition. 
   
   
       29 . The process of  claim 16 , wherein (b) is present in the composition in an amount of from about 0.2 to about 10% by weight, based on the total weight of the composition. 
   
   
       30 . The process of  claim 16  wherein the composition comprises: (a) about 2% by weight, phloretin; (b) about 0.5% by weight, ferulic acid; (c) about 15% by weight, ascorbic acid; (d) about 30% by weight of a glycol; and (e) remainder, to 100%, water.