Method and composition for burned skin

Abstract

The present invention is directed to the use of an agent selected from ethyl alcohol, isopropyl alcohol or a mixture thereof and a topically acceptable polymeric carrier in the preparation of a composition for the treatment of burns.

1 - 18 . (canceled)  
     
     
         19 . A method for treating and/or impeding progression of burns, comprising applying to the burned area a composition comprising ethyl alcohol and a topically acceptable polymeric carrier, wherein the concentration of said ethyl alcohol is in the range of 15-50% of the total weight of said composition.  
     
     
         20 . A method according to  claim 19 , wherein the concentration of the ethyl alcohol in the composition is in the range of 20% to 50%.  
     
     
         21 . A method according to  claim 19 , wherein the topically acceptable carrier comprises a polymer which forms a gel like matrix with the alcohol.  
     
     
         22 . A method according to  claim 21 , wherein the polymer forming gel like matrix is an acidic polymer or a salt thereof.  
     
     
         23 . A method according to  claim 22 , wherein the acidic polymer is an acrylic polymer.  
     
     
         24 . A method according to  claim 23 , wherein the acrylic polymer is a carbopol®.  
     
     
         25 . A method according to  claim 23 , wherein the acrylic polymer is at least partially neutralized with a base to form a salt thereof.  
     
     
         26 . A method according to  claim 25 , wherein the base is a nitrogen containing base.  
     
     
         27 . A method according to  claim 26 , wherein the base is selected from the group consisting of ammonium hydroxide, dialkanolamines and trialkanolamines.  
     
     
         28 . A method according to  claim 27 , wherein the composition comprises ethanol in a concentration of 15-50% w/w, polyacrylate in a concentration of 0.05%-5% and ammonium hydroxide in a concentration of 0.1-10%.  
     
     
         29 . A method according to  claim 28 , wherein the composition comprises ethanol in a concentration of 20-50% w/w, polyacrylate in a concentration of 0.05%-5% and triethanolamine in a concentration of 0.1-6%.  
     
     
         30 . A method according to  claim 19 , wherein the composition further comprises urea.  
     
     
         31 . A method according to  claim 19 , wherein said composition further comprises plants-derived material.  
     
     
         32 . A method according to  claim 31 , wherein the plant derived material is in the form of plant extracts, tinctures, oils and/or macerates.  
     
     
         33 . A method according to  claim 32 , wherein the plant is selected from the group consisting of arnica, plantago, equisetum, lavender, joubarbe, hamamelis, urtica, calendula, daucus, symphytum, sanguisorba, symphytum, aloe vera, roman chamomile, tea tree, witch hazel, Emu, Celosia Argentea and mameluca.  
     
     
         34 . A method according to  claim 19 , wherein the composition is provided in the form of a gel, cream, emulsion, lotion, suspension, liposomes, ethosomes, microcapsules or microspheres.  
     
     
         35 . A method according to  claim 19 , wherein the composition further comprises one or more ingredients selected from the group consisting of a local anesthetic, antibiotic, plant extract, vitamin, growth factor, protein, histamine, carnosine, insulin, anti-inflammatory agent, antiseptic agent, antifungal agent, anticytokine, an interleukin, growth hormone and re-epithelization factors.  
     
     
         36 . A method according to  claim 19 , wherein the topically acceptable carrier comprises one or more of the following polymers: chitin, guar, chitosan, polyvinylpyrrolidone, polyvinylalcohol, gum, silastic, eudragit, pectin, hyaluronic acid, hyaluronate, gelatin, gelatin derivative, agar, polymer adhesives, polaxomers, a cellulose derivative, including methylcelluose, ethylcellulose, hydroxypropylcellulose and hydroxyethylcellulose, or a mixture of said excipients.