US2007026045A1PendingUtilityA1

Reinforced matrices

Assignee: ASCULAI SAMUELPriority: May 8, 2001Filed: Oct 5, 2006Published: Feb 1, 2007

Est. expiryMay 8, 2021(expired)· nominal 20-yr term from priority

Inventors:Samuel Simon Asculai Bruno Giannetti

A61K 38/012A61K 35/32A61L 27/3843A61L 27/3817A61L 27/26

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Claims

Abstract

A reinforced matrix membrane containing one or more scaffold-forming proteins suitable for cell growth and for use in chondrocyte cell transplantation, and method of making same. The scaffold is incubated with the collagen matrix in solutions, colloidal dispersions, or suspensions of stabilizing proteins. The reinforced matrix may be used in tissue engineering, cartilage transplantation, bone and cartilage grafting, healing, joint repair and the prevention of arthritic pathologies.

Claims

exact text as granted — not AI-modified

1 - 21 . (canceled)  
     
     
         22 . An implantable article comprising: 
 (a) chondrocytes; and    (b) a fleece membrane comprising hyaluronic acid and elastin;    wherein said chondrocytes are on a surface of said fleece membrane prior to implantation.    
     
     
         23 . The article of  claim 22 , wherein said hyaluronic acid is cross-linked.  
     
     
         24 . The article of  claim 22 , wherein the chondrocyte cell concentration is about 1×10 5  cells/milliliter.

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