US2007026039A1PendingUtilityA1

Composite self-cohered web materials

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Individually held — no corporate assignee on recordPriority: Jul 29, 2005Filed: Jul 29, 2005Published: Feb 1, 2007
Est. expiryJul 29, 2025(expired)· nominal 20-yr term from priority
Inventors:Paul D. DrumhellerTed R. FarnsworthCharles FlynnByron K. HayesCharles F. White
Y10T442/10A61B 17/07292Y10T428/1376A61P 29/00A61L 31/16A61L 31/06Y10T428/1317A61L 31/129A61L 27/56A61L 27/48A61L 27/54A61L 27/18A61L 2300/606A61L 31/146
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Claims

Abstract

The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.

Claims

exact text as granted — not AI-modified
1 . An implantable article comprising melt-formed continuous filaments intermingled to form a porous web wherein said filaments are self-cohered to each other at multiple contact points, wherein said filaments comprise at least one semi-crystalline polymeric component covalently bonded to or blended with at least one amorphous polymeric component, wherein the filaments possess partial to full polymeric component phase immiscibility when in a crystalline state, and a hydrogel material placed on at least one of said filaments.  
   
   
       2 . The implantable article of  claim 1  wherein the hydrogel is cross-linked.  
   
   
       3 . The implantable article of  claim 1  wherein said hydrogel material fills at least part of at least one void space present between said filaments.  
   
   
       4 . The implantable article of  claim 3  wherein the hydrogel is cross-linked  
   
   
       5 . The implantable article of  claim 1  wherein said implantable article has a percent porosity greater than ninety in the absence of additional components.  
   
   
       6 . The implantable article of  claim 1  wherein said implantable article has a percent porosity greater than ninety in the absence of additional components.  
   
   
       7 . The implantable article of  claim 1  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       8 . The implantable article of  claim 1  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       9 . The implantable article of  claim 1  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       10 . The implantable article of  claim 2  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       11 . The implantable article of  claim 2  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       12 . The implantable article of  claim 2  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       13 . The implantable article of  claim 3  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       14 . The implantable article of  claim 3  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       15 . The implantable article of  claim 3  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       16 . The implantable article of  claim 1  further comprising a bioactive species in combination with the hydrogel material.  
   
   
       17 . The implantable article of  claim 16  wherein the bioactive species comprises an anti-inflammatory.  
   
   
       18 . The implantable article of  claim 17  wherein the anti-inflammatory is dexamethasone.  
   
   
       19 . The implantable article of  claim 2  further comprising a bioactive species in combination with the cross-linked hydrogel material.  
   
   
       20 . The implantable article of  claim 19  wherein the bioactive species comprises an anti-inflammatory.  
   
   
       21 . The implantable article of  claim 20  wherein the anti-inflammatory is dexamethasone.  
   
   
       22 . The implantable article of  claim 3  further comprising a bioactive species in combination with the hydrogel material.  
   
   
       23 . The implantable article of  claim 22  wherein the bioactive species comprises an anti-inflammatory.  
   
   
       24 . The implantable article of  claim 23  wherein the anti-inflammatory is dexamethasone.  
   
   
       25 . The implantable article of  claim 4  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       26 . The implantable article of  claim 4  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       27 . The implantable article of  claim 4  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       28 . The implantable article of  claim 4  further comprising a bioactive species in combination with the cross-linked hydrogel material.  
   
   
       29 . The implantable article of  claim 28  wherein the bioactive species comprises an anti-inflammatory.  
   
   
       30 . The implantable article of  claim 29  wherein the anti-inflammatory is dexamethasone.  
   
   
       31 . An implantable article comprising melt-formed continuous filaments intermingled to form a porous web wherein said filaments are self-cohered to each other at multiple contact points, wherein said filaments comprise a first semi-crystalline polymeric component covalently bonded to or blended with at least one additional semi-crystalline polymeric component, wherein the filaments possess partial to full polymeric component phase immiscibility when in a crystalline state, and a hydrogel material placed on at least one of said filaments.  
   
   
       32 . The implantable article of  claim 31  wherein the hydrogel material is cross-linked.  
   
   
       33 . The implantable article of  claim 31  wherein said hydrogel material fills at-least part of at least one void space present between said filaments.  
   
   
       34 . The implantable article of  claim 33  wherein the hydrogel material is cross-linked.  
   
   
       35 . The implantable article of  claim 31  wherein said implantable article has a percent porosity greater than ninety in the absence of additional components.  
   
   
       36 . The implantable article of  claim 31  wherein the percent porosity is greater than ninety-one in the absence of additional components.  
   
   
       37 . The implantable article of  claim 31  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       38 . The implantable article of  claim 31  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       39 . The implantable article of  claim 31  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       40 . The implantable article of  claim 32  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       41 . The implantable article of  claim 32  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       42 . The implantable article of  claim 32  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       43 . The implantable article of  claim 33  wherein said hydrogel material comprises polyvinyl alcohol.  
   
   
       44 . The implantable article of  claim 33  wherein said hydrogel material comprises carboxymethylcellulose.  
   
   
       45 . The implantable article of  claim 33  wherein said hydrogel material comprises a co-polymer of polyethylene glycol and polypropylene glycol.  
   
   
       46 . The implantable article of  claim 31  further comprising a bioactive species in combination with the hydrogel material.  
   
   
       47 . The implantable article of  claim 46  wherein the bioactive species comprises an anti-inflammatory.  
   
   
       48 . The implantable article of  claim 47  wherein the anti-inflammatory is dexamethasone.  
   
   
       49 . The implantable article of  claim 42  further comprising a bioactive species in combination with the cross-linked hydrogel material.  
   
   
       50 . The implantable article of  claim 49  wherein the bioactive species comprises an anti-inflammatory.  
   
   
       51 . The implantable article of  claim 50  wherein the anti-inflammatory is dexamethasone.

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