US2007026012A1PendingUtilityA1

Compositions and methods for monitoring and altering protein folding and solubility

49
Assignee: UNIV CORNELLPriority: Aug 1, 2005Filed: Aug 1, 2005Published: Feb 1, 2007
Est. expiryAug 1, 2025(expired)· nominal 20-yr term from priority
Inventors:Matthew P. DelisaAdam Fisher
C12N 15/1086C07K 2319/034C12N 15/1034C12N 15/625C12N 15/62
49
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present invention relates to the fields of microbiology, molecular biology and protein biochemistry. More particularly, it relates to compositions and methods for analyzing and altering (e.g., enhancing or inhibiting) protein folding and solubility.

Claims

exact text as granted — not AI-modified
1 . A composition comprising a fusion protein, wherein said fusion protein comprises a ssTorA signal peptide, an antibody and a TEM1 β-lactamase.  
     
     
         2 - 24 . (canceled)  
     
     
         25 . The composition of  claim 1 , wherein said antibody is selected from the group consisting of an immunoglobulin light chain, antibodies, antibody fragments (such as single-chain Fv fragment (scFv), single-chain antibody (scAb), F AB  antibody fragment.  
     
     
         26 . The composition of  claim 25 , wherein said antibody is a human antibody.

Join the waitlist — get patent alerts

Track US2007026012A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.