US2007010009A1PendingUtilityA1

Antibody Composition-Producing Cell

Assignee: KYOWA HAKKO KOGYO KKPriority: Oct 6, 2000Filed: Apr 13, 2006Published: Jan 11, 2007

Est. expiryOct 6, 2020(expired)· nominal 20-yr term from priority

Inventors:Yutaka Kanda Mitsuo Satoh Kazuyasu Nakamura Kazuhisa Uchida Toyohide Shinkawa Naoko Yamane Emi Hosaka Kazuya Yamano Motoo Yamasaki Nobuo Hanai

A61P 37/08A61P 37/00A61P 37/02A61P 29/00A61P 31/12A61P 31/04A61P 35/00C07K 16/1145C07K 16/18C07K 16/2887C12Y 204/01068C12N 9/0006C07K 16/32C07K 2317/24C07K 2317/565C07K 16/2866C07K 16/3084C12N 9/90C12N 15/8257C12N 15/8258C07K 16/44C12N 15/8245C12N 9/1051C07K 16/2812C07K 16/2896C07K 2317/732C12P 21/00C07K 2317/41C07K 16/2863C12P 21/005C07K 16/241C07K 2319/30

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Abstract

The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.

Claims

exact text as granted — not AI-modified

1 . A cell into which a gene encoding an antibody composition is introduced, which is resistant to a lection which recognizes a sugar chain in which 1-position of fucose is bound to 6-position of N-acetylglucosamine in the reducing end through α-bond in a complex N-glycoside-linked sugar chain.

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