US2006293236A1PendingUtilityA1
Injectable Osteogenic Formula and Method of Using Same
Individually held — no corporate assignee on recordPriority: Jun 23, 2005Filed: Jun 23, 2006Published: Dec 28, 2006
Est. expiryJun 23, 2025(expired)· nominal 20-yr term from priority
A61K 31/557A61K 31/728A61K 38/16A61K 9/0019A61K 47/36A61K 31/5575
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Claims
Abstract
Formulations and methods for growing bone in a site specific location using an osteogenic molecule such as a prostaglandin, and a delivery vehicle which is preferably a polymer matrix.
Claims
exact text as granted — not AI-modified1 . An osteogenic formulation, comprising:
an osteogenic compound; and a delivery vehicle.
2 . The osteogenic formulation of claim 1 , wherein the compound comprises prostaglandin (PGE).
3 . The osteogenic formulation of claim 2 in which the compound is PGE1.
4 . The osteogenic formulation of claim 2 in which the compound is PGE2.
5 . The osteogenic formulation of claim 1 , wherein the delivery vehicle comprises a biodegradable matrix.
6 . The osteogenic formulation of claim 5 , wherein the biodegradable matrix comprises a polymer.
7 . The osteogenic formulation of claim 6 , wherein the polymer comprises hyaluronic acid or a salt thereof.
8 . The osteogenic formulation of claim 6 , wherein the polymer comprises a poly-glutamic acid.
9 . An osteogenic formulation, comprising:
prostaglandin (PGE) osteogenic compound; and a biodegradable polymer matrix delivery vehicle for the PGE.
10 . The osteogenic formulation of claim 9 , wherein the polymer comprises hyaluronic acid or a salt thereof.
11 . The osteogenic formulation of claim 9 , wherein the polymer comprises a poly-glutamic acid.
12 . A method of employing an osteogenic compound, comprising:
providing prostaglandin (PGE) osteogenic compound; providing a biodegradable polymer matrix delivery vehicle for the PGE; mixing the PGE and the delivery vehicle; and delivering the mixture to a site.
13 . The method of claim 12 in which the PGE comprises PGE1.
14 . The method of claim 12 in which the PGE comprises PGE2.
15 . The method of claim 12 in which the polymer comprises hyaluronic acid or a salt thereof.
16 . The method of claim 12 in which the polymer comprises a poly-glutamic acid.
17 . The method of claim 12 in which delivery is accomplished with a syringe.
18 . A method of employing an osteogenic compound, comprising:
providing prostaglandin (PGE) osteogenic compound; providing a biodegradable polymer matrix delivery vehicle for the PGE comprising hyaluronic acid or a salt thereof; mixing the PGE and the delivery vehicle; and delivering the mixture to a site with a syringe.Join the waitlist — get patent alerts
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