Anti fibrotic agent containing sphingosine 1-phosphate receptor agonist or sphingosine 1-phosphate as active ingredient

Abstract

An anti fibrotic agent, comprising a sphingosine 1-phosphate (S1P) receptor agonist or sphingosine 1-phosphate (S1P) as an active ingredient. Since an S1P receptor agonist, particularly S1P, has activity of inhibiting fibrosis in various organs, it is useful in preventing and/or treating diseases caused by fibrosis in organs, such as pulmonary fibrosis, interstitial pneumonia, chronic hepatitis, hepatic cirrhosis, chronic renal failure, renal glomerulosclerosis, etc.

1 . (canceled)  
   
   
       2 . A method for treating a fibrosis, said method comprising administering an effective amount of an agent comprising a sphingosine 1-phosphate receptor agonist as an active ingredient.  
   
   
       3 . The method for according to  claim 2 , wherein the fibrosis is pulmonary fibrosis, interstitial pneumonia, chronic hepatitis, hepatic cirrhosis, chronic renal failure or renal glomerulosclerosis.  
   
   
       4 .- 6 . (canceled)  
   
   
       7 . A method for treating interstitial pneumonia, chronic hepatitis, hepatic cirrhosis, chronic renal failure or renal glomerulosclerosis, said method comprising administering to a subject in need of treatment an effective amount of an agent comprising a sphingosine 1-phosphate as an active ingredient.