Pharmacologically active strong acid solutions

Abstract

A composition and therapeutic methods therefore for pharmacologically strong acid solutions comprising a mixture of strong and weak acids.

1 . A method of disinfecting comprising the administration or application of a composition comprising a mixture of three strong acids and three weak acids.  
     
     
         2 . The method of  claim 1  wherein at least one (1) of the weak acids is hydrofluoric acid.  
     
     
         3 . The method of  claim 1  wherein the acids are selected from the group consisting of sulfuric, hydrochloric, oxalic, phosphoric, citric and hydrofluoric acids.  
     
     
         4 . The method of  claim 1  wherein the acids are present in the following concentrations by weight:  
       
         
           
                 
                 
                 
               
                     
                     
                 
                     
                     
                 
                     
                   HCl 
                   3-25% 
                 
                     
                   H 2 C 2 O 4   
                   0.1-10%   
                 
                     
                   H 3 PO 4   
                   3-10% 
                 
                     
                   HF 
                   1-30% 
                 
                     
                     
                 
                     
                     
                 
             
                
                
               
               
                
                
                
                
                
                
               
            
           
         
       
     
     
         5 . The composition of  claim 1  wherein the acids are present in the following concentrations by weight:  
       
         
           
                 
                 
                 
               
                     
                     
                 
                     
                     
                 
                     
                   HCl 
                    5-15% 
                 
                     
                   H 2 C 2 O 4   
                   0.15-2%   
                 
                     
                   H 3 PO 4   
                   2-7% 
                 
                     
                   HF 
                   2-7% 
                 
                     
                     
                 
                     
                     
                 
             
                
                
               
               
                
                
                
                
                
                
               
            
           
         
       
     
     
         6 . The composition of  claim 1  wherein the acids are present in the following approximate concentrations by weight:  
       
         
           
                 
                 
                 
               
                     
                     
                 
                     
                     
                 
                     
                   HCl 
                    11% 
                 
                     
                   H 2 C 2 O 4   
                   0.3% 
                 
                     
                   H 3 PO 4   
                     6% 
                 
                     
                   H 2 SO 4   
                    16% 
                 
                     
                   HF 
                     5% 
                 
                     
                   H 8 C 6 O 7   
                   0.3% 
                 
                     
                     
                 
                     
                     
                 
             
                
                
               
               
                
                
                
                
                
                
                
                
               
            
           
         
       
     
     
         7 . The method of  claim 1  wherein the acid composition further comprises glycerin.  
     
     
         8 . The composition of claim one wherein the composition has a pH of below 1 before dilution.  
     
     
         9 . The method of  claim 1  wherein infection is reduced or prevented in a circulatory access port.  
     
     
         10 . The method of  claim 9  wherein the acid composition is administered by means of the circulatory access port.  
     
     
         11 . The method of  claim 9  wherein the acid composition is administered intravenously.  
     
     
         12 . The method of  claim 9  wherein the circulatory access port is selected from the group consisting of: stents, peripheral catheters and central catheters.  
     
     
         13 . The method of  claim 9  wherein the circulatory access port is a subclavian catheter.  
     
     
         14 . A method of treating infection in a patient in need thereof comprising the administration of an effective amount of a strong acid buffer comprising a mixture of three strong acids and three weak acids.  
     
     
         15 . The method of  claim 14  wherein at least one (1) of the weak acids is hydrofluoric acid.  
     
     
         16 . The method of  claim 14  wherein the acids are selected from the group consisting of sulfuric, hydrochloric, oxalic, phosphoric, citric and hydrofluoric acids.  
     
     
         17 . The method of  claim 14  wherein the acids are present in the following concentrations by weight prior to dilution:  
       
         
           
                 
                 
                 
               
                     
                     
                 
                     
                     
                 
                     
                   HCl 
                   3-25% 
                 
                     
                   H 2 C 2 O 4   
                   0.1-10%   
                 
                     
                   H 3 PO 4   
                   3-10% 
                 
                     
                   HF 
                   1-30% 
                 
                     
                     
                 
                     
                     
                 
             
                
                
               
               
                
                
                
                
                
                
               
            
           
         
       
     
     
         18 . The method of  claim 14  wherein the acids are present in the following concentrations by weight prior to dilution:  
       
         
           
                 
                 
                 
               
                     
                     
                 
                     
                     
                 
                     
                   HCl 
                   >5-15% 
                 
                     
                   H 2 C 2 O 4   
                   0.15-2%   
                 
                     
                   H 3 PO 4   
                   2-7% 
                 
                     
                   HF 
                   2-7% 
                 
                     
                     
                 
                     
                     
                 
             
                
                
               
               
                
                
                
                
                
                
               
            
           
         
       
     
     
         19 . A method of preventing growth of microorganisms in a substance comprising the addition of the composition of  claim 1  to the substance.  
     
     
         20 . The method of  claim 19 , wherein the substance comprises a tissue culture.