US2006229331A1PendingUtilityA1

Ketoprofen compositions and methods of making them

61
Individually held — no corporate assignee on recordPriority: Dec 13, 2002Filed: Jun 19, 2006Published: Oct 12, 2006
Est. expiryDec 13, 2022(expired)· nominal 20-yr term from priority
Inventors:Ronald Haas
A61K 9/0095A61K 9/0014A61K 9/0019A61K 9/02A61K 47/10
61
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Claims

Abstract

A wide variety of pharmaceutically and commercially acceptable dosage forms of ketoprofen are prepared by dissolving ketoprofen in pharmaceutically acceptable solvents.

Claims

exact text as granted — not AI-modified
1 . A clear and stable aqueous solution, comprising a predetermined therapeutically effective amount of an alkali metal salt of ketoprofen dissolved in an aqueous medium.  
   
   
       2 . The aqueous solution of  claim 1 , in which the therapeutically effective amount of ketoprofen salt is a mass equivalent of about 12.5 mgs to 150 mgs of ketoprofen per 5 ml of aqueous solution.  
   
   
       3 . The aqueous solution of  claim 1 , in which there is no particulate matter evident in the solution upon visual examination.  
   
   
       4 . A palatable solution in accordance with  claim 1 , which has a substantially reduced flavor of ketoprofen without additional flavoring agents.  
   
   
       5 . The solution of  claim 1 , further comprising a flavoring agent.  
   
   
       6 . The solution of  claim 1 , further comprising a sweetening agent.  
   
   
       7 . The solution of  claim 1 , further comprising sucrose.  
   
   
       8 . The solution of  claim 1 , further comprising sorbitol.  
   
   
       9 . The solution of  claim 1 , further comprising glycerin.  
   
   
       10 . The solution of  claim 1 , further comprising artificial sweetener.  
   
   
       11 . The solution of  claim 10 , in which the artificial sweetener is saccharine.  
   
   
       12 . The solution of  claim 1 , further comprising a preservative composition.  
   
   
       13 . A colorless solution in accordance with  claim 1 .  
   
   
       14 . A pharmaceutically acceptable and palatable oral dosage form of ketoprofen comprising the solution of  claim 1 .  
   
   
       15 . The solution of  claim 1 , further comprising an additional medication.  
   
   
       16 . The solution of  claim 15 , in which the additional medication is a narcotic composition.  
   
   
       17 . The solution of  claim 16 , in which the narcotic composition is hydrocodone.

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