US2006223112A1PendingUtilityA1
Novel receptor
Individually held — no corporate assignee on recordPriority: Sep 7, 1998Filed: Oct 6, 2005Published: Oct 5, 2006
Est. expirySep 7, 2018(expired)· nominal 20-yr term from priority
C07K 16/28G01N 2500/00C07K 14/70571A61K 38/00G01N 33/9426
46
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Claims
Abstract
The present invention relates to the novel GABA B receptor subtypes GABA B -R1c and GABA B -R2 as well as to a novel, functional GABA B receptor which comprises a heterodimer of GABA B -R1 and GABA B -R2 receptor subunits. The present invention also relates to variants of the receptors, nucleotide sequences encoding the receptors and variants thereof and novel vectors, stable cell lines, antibodies, screening methods, methods of treatment and methods of receptor production.
Claims
exact text as granted — not AI-modified1 - 37 . (canceled)
38 . A method for identification of a compound which exhibits GABAb receptor modulating activity, comprising contacting the GABAb receptor with a test compound and detecting modulating activity or inactivity, wherein said GABAb receptor comprises a heterodimer between a GABAb-R1 receptor protein and a GABAb-R2 receptor protein wherein the GABAb-R1 comprises the no acid sequence for GABAb-R1a, GABAb-R1b or GABAb-R1c as set forth in FIG. 2 and wherein the GABAb-R2 receptor comprises the amino acid sequence set forth in FIG. 1 b.
39 - 46 . (canceled)Join the waitlist — get patent alerts
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