Method and reagent for detecting cell death

Abstract

A method for detecting cell death, which comprises determining cytochrome C in body fluid and detecting cell death based on a quantified value, as well as a method for determining cytochrome C in body fluid by a sandwich method and a reagent for measuring cytochrome C for determination cytochrome C in body fluid by a sandwich method, which comprises an antibody directed to cytochrome C as an ingredient.

1 - 3 . (canceled)  
   
   
       4 . A reagent for measuring cytochrome C for determination of cytochrome C in body fluid by a sandwich method, which comprises an antibody directed to cytochrome C as an ingredient.  
   
   
       5 . The reagent for measuring cytochrome C according to  claim 4 , which is used for detection of cell death.  
   
   
       6 . The reagent for measuring cytochrome C according to  claim 4 , which is used for diagnosis of graft versus host disease.  
   
   
       7 . The reagent for measuring cytochrome C according to  claim 4 , which is used for diagnosis of hemophagocytic syndrome.  
   
   
       8 . The reagent for measuring cytochrome C according to  claim 4 , which is used for diagnosis of acute lymphatic leukemia.  
   
   
       9 . The reagent for measuring cytochrome C according to  claim 4 , which is used for diagnosis of viral encephalitis or encephalopathy.  
   
   
       10 . The reagent for measuring cytochrome C according to  claim 9 , wherein the viral encephalitis or encephalopathy is influenzal encephalitis or encephalopathy.