US2006153802A1PendingUtilityA1

Mammalian chemokine reagents

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Individually held — no corporate assignee on recordPriority: Dec 8, 1995Filed: Mar 20, 2006Published: Jul 13, 2006
Est. expiryDec 8, 2015(expired)· nominal 20-yr term from priority
Inventors:Daniel DairaghiTakahiko HaraAtsushi MiyajimaThomas SchallWei WangAkihiko Yoshimura
C07K 14/523C07K 14/521C07K 14/7158A61K 38/00C07K 2319/00
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Claims

Abstract

A novel CC chemokine which is from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokine. A chemokine receptor is also provided. Methods of using said reagents and diagnostic kits are also provided.

Claims

exact text as granted — not AI-modified
1 . An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 4.  
     
     
         2 . A fusion protein comprising the polypeptide of  claim 1  fused to a heterologous protein.  
     
     
         3 . The fusion protein of  claim 2  wherein the heterologous protein is a member selected from the group consisting of bacterial β-galactosidase, trpE, protein A, β-lactamase, alpha amylase, alcohol dehydrogenase, FLAG, yeast alpha mating factor and luciferase.  
     
     
         4 . The polypeptide of  claim 1  which is chemically labeled.  
     
     
         5 . The polypeptide of  claim 1  wherein the label is a member selected from the group consisting of phosphate, sulfate and biotin.  
     
     
         6 . The polypeptide of  claim 1  which is glycosylated.  
     
     
         7 . The polypeptide of  claim 1  which is deglycosylated.  
     
     
         8 . A composition comprising the polypeptide of  claim 1  and a pharmaceutically acceptable carrier.

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