US2006142557A1PendingUtilityA1

2'-deoxy-2'alkylnucleotide containing nucleic acid

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Assignee: SIRNA THERAPEUTICS INCPriority: Mar 29, 1994Filed: Feb 27, 2006Published: Jun 29, 2006
Est. expiryMar 29, 2014(expired)· nominal 20-yr term from priority
Inventors:Nassim UsmanAlexander KarpeiskyLeonid BeigelmanAnil Modak
C07H 21/04C07H 19/04C12N 2310/333C12N 2310/121C07H 21/02C12N 15/1138C12N 15/1136C12N 2310/126C12N 2310/3513C12N 15/113C12N 2310/127C12N 2310/3535C12N 2310/3523C12N 15/1131C12N 2310/336C12N 2310/32C12N 2310/111C12N 2310/123C12N 2310/322C12N 2310/3527C12N 2310/122C12N 2310/1241A61K 48/00A61K 38/00C12N 2310/335C12N 2310/334C12N 15/101C12N 2310/3533C07H 19/048
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Claims

Abstract

2′-deoxy-2′-alkylnucleotides useful for stabilizing enzymatic nucleic acid molecules and antisense molecules.

Claims

exact text as granted — not AI-modified
1 . 2′-deoxy-2′-C-allyl nucleoside.  
     
     
         2 . 2′-deoxy-2′-C-allyl nucleotide.  
     
     
         3 . An oligonucleotide comprising one or more 2′-C-allyl nucleotide.  
     
     
         4 . The oligonucleotide of  claim 3 , wherein said oligonucleotide is single stranded.  
     
     
         5 . The oligonucleotide of  claim 3 , wherein said oligonucleotide is double stranded.

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