Use of a container of an inorganic additive containing plastic material

Abstract

The present invention relates to the use of a container, made of an inorganic additive containing plastic material, for reducing physical/chemical interaction between the container and an oil, fat and/or wax containing formulation contained therein.

1 . Use of a container, made of an inorganic additive containing plastic material, for reducing physical/chemical interaction between the container and an oil, fat and/or wax containing formulation contained therein.  
     
     
         2 . Use of the container according to  claim 1  wherein the physical/chemical interaction is an adsorption of the formulation to the plastic material.  
     
     
         3 . Use according to  claim 1 , wherein the inorganic additive is at least a pigment.  
     
     
         4 . Use according to  claim 3 , wherein the at least one pigment is titanium dioxide (TiO 2 ), surface-treated titanium dioxide, or a mixture thereof.  
     
     
         5 . Use according to  claim 1 , wherein the additive is present in the plastic material in an amount between 0.1 and 10% by weight, more preferably between 0.1 and 5% by weight, and most preferably about 2% by weight, based on the weight of the plastic material.  
     
     
         6 . Use according to  claim 1 , wherein the plastic material comprises polyolefin.  
     
     
         7 . Use according to  claim 6 , wherein the polyolefin is selected from the group of polyethylene, polypropylene, copolymers of ethylene and propylene, or a mixture thereof.  
     
     
         8 . Use according to  claim 7 , wherein the plastic material comprises low density polyethylene (LDPE).  
     
     
         9 . Use according to  claim 1 , wherein the plastic material is suitable for extrusion blow molding.  
     
     
         10 . Use according to any of the preceding claims  claim 1 , wherein the formulation comprises at least one steroid hormone dissolved or suspended in oil, fat and/or wax.  
     
     
         11 . Use according to  claim 10 , wherein the steroid hormone is a sexual hormone drug, preferably testosterone, and the formulation further comprises at least one lipophilic or partially lipophilic carrier; and a compound or a mixture of compounds having surface tension decreasing activity, in an amount effective for in situ generation of an emulsion upon contact of the formulation with water.  
     
     
         12 . Use according to  claim 1 , wherein the formulation is for nasal application, preferably to a mammalian.