US2006121118A1PendingUtilityA1

Antimycotic gel having high active compound release

Assignee: AVENTIS PHARMA GMBHPriority: Sep 27, 1996Filed: Jan 31, 2006Published: Jun 8, 2006
Est. expirySep 27, 2016(expired)· nominal 20-yr term from priority
A61P 31/10A61P 31/00A61P 17/00A61K 47/10A61K 47/32A61K 47/38A61K 31/4412A61K 9/0014A61K 31/44
55
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Claims

Abstract

A pharmaceutical preparation comprising a hydrophilic gel-forming agent, water and a compound of the formula I is suitable for the treatment and prophylaxis of dermatomycoses.

Claims

exact text as granted — not AI-modified
1 - 11 . (canceled)  
   
   
       12 . A gel composition comprising: 
 at least one hydrophilic gel-forming agent;    at least one spreading agent; and    an active component consisting essentially of at least one compound chosen from a compound of formula (I) and physiologically tolerable salts thereof:                          wherein R 1 , R 2 , and R 3 , which are identical or different, are a hydrogen atom or alkyl group having 1 to 4 carbon atoms, and R 4  is a saturated hydrocarbon radical having 6 to 9 carbon atoms;    wherein the composition is substantially free of any additional active components, and    wherein the composition is not an emulsion.    
   
   
       13 . A gel composition of  claim 12 , wherein the active component consists essentially of 1-hydroxy-4-methyl-6-cyclohexyl-2(1H)pyridone, at least one physiologically tolerable salt thereof, or a mixture thereof.  
   
   
       14 . A gel composition of  claim 12 , wherein the active component consists essentially of 1-hydroxy-4-methyl-6-(2,4,4,-trimethylpentyl)-2(1H)pyridone, at least one physiologically tolerable salt thereof, or a mixture thereof.

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