Chromatography columns

Abstract

The present invention relates to a chromatography column that removes the longitudinal load from the column tube altogether and transfers it to a yoke and stanchion arrangement situated around but external to the column tube. By using the yoke/stanchion system, the central adjuster can be used to move the top end into and out of the housing. Thus, when internal pressure is applied to the column, the tube experiences no longitudinal load. Additionally, the yoke and stanchion design allows for complete removal of the end from the tube without cumbersome disassembly. Moreover, the yoke provides a place to retain the end while the tube is being filled, emptied, cleaned or repaired.

1 ) A chromatography column comprising a column tube and a external set of two or more stanchions and a yoke connected to the two or more stanchions to carry any longitudinal loads imposed on the chromatography column.  
   
   
       2 ) A chromatography column comprising a base plate, column tube, a bottom edge of the column tube being attached in a liquid tight sealing arrangement to the base plate, a top plate and a bottom plate mounted at respective ends of the column tube the base plate having a diameter greater than that of the column tube, two or more stanchions mounted to the base plate around but external to the column tube and a yoke connected to the two or more stanchions, a central adjuster formed on the yoke and being attached to the top plate and wherein the yoke and two or more stanchions support the longitudinal loads imposed on the chromatography column.  
   
   
       3 ) A chromatography column comprising a base plate, column tube, a bottom edge of the tube being attached in a liquid tight sealing arrangement to the base plate, the base plate having diameter greater than that of the tube, two or more stanchions, each having a lower end and an upper end, the lower ends being attached to the base plate external of the tube, a yoke connected to the two or more stanchions such that it spans the width and centerline of the tube, a central adjuster is formed on the yoke over the centerline of the tube, the adjuster being movably connected to a top surface of a column top end plate so that the top end plate may move into and out of the tube interior and wherein the yoke and two or more stanchions removes the longitudinal load from the column tube and transfers it to yoke and two or more stanchions.  
   
   
       4 ) The column of  claim 3  wherein the yoke is selectively attached to the two or more stanchions for removal.  
   
   
       5 ) The column of  claim 3  wherein the yoke is selectively attached to the two or more stanchions such that it may be pivoted away from the centerline of the tube when the top plate has been retracted from the tube.  
   
   
       6 ) The column of  claim 3  wherein the yoke is selectively attached to the two or more stanchions such that it may be pivoted away vertically from the centerline of the tube when the top plate has been retracted from the tube.  
   
   
       7 ) The column of  claim 3  wherein the yoke is selectively attached to the two or more stanchions such that it may be pivoted away horizontally from the centerline of the tube when the top plate has been retracted from the tube.  
   
   
       8 ) The column of  claim 3  wherein the yoke is selectively attached to the two or more stanchions for removal by a retainer selected from the group consisting of nuts and bolts, clevis pins, cotter pins and clamps.  
   
   
       9 ) The column of  claim 3  wherein the yoke and two or more stanchions allow one to remove or repair of the top plate, tube or base plate of the column without complete disassembly of the column.  
   
   
       10 ) The column of  claim 3  wherein the two or more stanchions and the yoke allow one to remove or repair of the top plate, tube or bottom plate of the column without complete disassembly of the column.  
   
   
       11 ) The column of  claim 3  wherein the column tube is interchangeable without complete disassembly of the column.  
   
   
       12 ) The column of  claim 3  wherein the column tube, fixed plate and top plate are interchangeable without complete disassembly of the column and by which the column internal diameter size can be altered.  
   
   
       13 ) The column of  claim 3  wherein there are more than two stanchions equidistant apart from each other.  
   
   
       14 ) The column of  claim 3  wherein there are three stanchions.  
   
   
       15 ) The column of  claim 3  wherein the two or more stanchions are of the same height as the column tube.  
   
   
       16 ) The column of  claim 3  wherein the two or more stanchions are of a height greater than that of the column tube.  
   
   
       17 ) The column of  claim 1  wherein the yoke is selectively attached to the two or more stanchions for removal.  
   
   
       18 ) The column of  claim 1  wherein the yoke is selectively attached to the two or more stanchions such that it may be pivoted away from a centerline of the column tube.  
   
   
       19 ) The column of  claim 1  wherein there are more than two stanchions equidistant apart from each other.  
   
   
       20 ) The column of  claim 1  wherein the two or more stanchions are of the same height as the column tube.  
   
   
       21 ) The column of  claim 1  wherein the two or more stanchions are of a height greater than that of the column tube.  
   
   
       22 ) The column of  claim 1  wherein the yoke has an upwardly tapered profile in cross-section.  
   
   
       23 ) The column of  claim 3  wherein the yoke has an upwardly tapered profile in cross-section.  
   
   
       24 ) The column of  claim 1  wherein the yoke is selectively attached to the two or more stanchions such that it may be pivoted away from a centerline of the column tube and the yoke has a stop to limit a range of motion of the yoke.  
   
   
       25 ) The column of  claim 3  wherein the yoke is selectively attached to the two or more stanchions such that it may be pivoted away from a centerline of the column tube and the yoke has a stop to limit a range of motion of the yoke.