US2006088933A1PendingUtilityA1

Reagents for detecting efavirenz

Individually held — no corporate assignee on recordPriority: Apr 22, 2003Filed: Oct 21, 2005Published: Apr 27, 2006

Est. expiryApr 22, 2023(expired)· nominal 20-yr term from priority

Inventors:Gerald Sigler Mitali Ghoshal Lili Arabshahi

C07D 265/18C07K 16/44A61K 47/646A61K 47/643A61P 31/18

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Claims

Abstract

The invention provides derivatives of efavirenz and methods of making derivatives of efavirenz. The derivatives include immunogenic compounds for producing antibodies to efavirenz and labeled efavirenz tracers. These compounds are useful in immunoassay methods for determining efavirenz.

Claims

exact text as granted — not AI-modified

1 . An antibody produced in response to a compound having the structure  
       
         
           
           
               
               
           
         
         wherein Y is a saturated or unsaturated, substituted or unsubstituted, straight or branched chain of up to 20 carbon atoms and heteroatoms;  
         Z is an immunogenic carrier; and  
         X is selected from the group consisting of halogens, NO 2 , NH 2 , CH 3 , and OCH 3 .  
       
     
     
         2 . The antibody of  claim 1  wherein X is Cl.  
     
     
         3 . The antibody of  claim 1  wherein Z is a carrier selected from the group consisting of poly(amino acids) and polysaccharides.

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