GANP protein

Abstract

The object of the present invention is to provide a novel protein having a kinase activity and a gene encoding said protein. According to the present invention, there is provided a GANP protein which is represented by the arnino acid sequence shown in SEQ ID No. 1 or No. 3 of the sequence listing, and is involved in the signal conversion of abnormal B cell differentiation in an autoimmune state, and has a kinase activity, and a polynucleotide which encodes said protein.

1 - 9 . (canceled)  
     
     
         10 . An antibody which recognizes the protein having the amino acid sequence shown in SEQ ID NO: 3.  
     
     
         11 . An antibody of a variant protein having a kinase activity substantially similar to an isolated protein having the amino acid sequence shown in SEQ ID NO: 3, wherein 1-20 amino acids are deleted, substituted, and/or added.