Nucleotide sequences for the control of the expression of DNA sequences in a cell host

Abstract

The present invention provides nucleotide sequences from Bacillus bacteria, which control the expression of other DNA sequences in a cell host.

1 - 43 . (canceled)  
     
     
         44 . An isolated DNA sequence comprising (a) a promoter sequence derived from the fragment comprising nucleotides 907 to 990 SEQ ID NO:1, (b) a region derived from a DNA sequence comprising nucleotides 979 to 1692, defined by the restriction sites HindIII-PstI (H3-P1) of SEQ ID NO:1, which enhances the expression in a host cell of a coding sequence placed downstream.  
     
     
         45 . An isolated DNA sequence, which hybridizes under stringent conditions, with a sequence according to  claim 44  and which enhances the expression of a nucleotide sequence placed downstream of the isolated DNA sequence.  
     
     
         46 . A recombinant DNA sequence comprising a sequence according to  claim 44  and a coding sequence downstream of said sequence, which is under the control of said promoter.  
     
     
         47 . A recombinant DNA sequence comprising a sequence according to  claim 45  and a coding sequence downstream of said sequence, which is under the control of said promoter.  
     
     
         48 . An expression vector comprising a DNA sequence according to  claim 44 .  
     
     
         49 . An expression vector comprising a DNA sequence according to  claim 45 .  
     
     
         50 . A recombinant cell host expressing DNA Sequence according to  claim 44 .  
     
     
         51 . A recombinant cell host expressing DNA Sequence according to  claim 46.