Sodium chondroitin sulfate, chondroitin-sulfate-containing material and processes for producing the same

Abstract

After a solution obtained by extracting protein from cartilages of fishes which are enzyme treated is filtered, alcohol is added to a filtrate to deposit sodium chondroitin sulfate. The sodium chondroitin sulfate manufactured thus can be used for a raw material of medicines, medicine derivatives, medicine additives, cosmetics, and food additives. After a solution obtained by extracting protein which is obtained by enzyme treatment of cartilages of fishes is filtered, the filtrate is dried to manufacture a chondroitin-sulfuric-acid-containing substance. The chondroitin-sulfuric-acid-containing substance manufactured thus is used for, for instance, cosmetics, and food materials.

1 . A method of manufacturing sodium chondroitin sulfate, comprising the steps of: 
 filtering an extracted solution of protein obtained by enzyme treatment of cartilages of fishes; and    precipitating sodium chondroitin sulfate by adding alcohol to said filtrate.    
   
   
       2 . The method of manufacturing sodium chondroitin sulfate according to  claim 1 , wherein alkali is added at the time of said enzyme treatment.  
   
   
       3 . The method of manufacturing sodium chondroitin sulfate according to claims  1 , further comprising the step of: 
 purifying sodium chondroitin sulfate deposited by adding alcohol.    
   
   
       4 . Sodium chondroitin sulfate being manufactured according to the method of  claim 1 .  
   
   
       5 . The sodium chondroitin sulfate according to  claim 4 , wherein said sodium chondroitin sulfate is used as a raw material of medicines, quasi medicines, medicine additives, cosmetics, or food additives.  
   
   
       6 . A method of manufacturing a chondroitin-sulfuric-acid-containing substance, comprising the steps of: 
 filtering an extracted solution of protein obtained by enzyme treatment of cartilages of fishes; and    drying said filtrate.    
   
   
       7 . A method of manufacturing a chondroitin-sulfuric-acid-containing substance, comprising the steps of: 
 filtering an extracted solution of protein obtained by enzyme treatment of cartilages of fishes;    precipitating a chondroitin-sulfuric-acid-containing substance by adding alcohol to said filtrate; and    drying said precipitated chondroitin-sulfuric-acid-containing substance.    
   
   
       8 . The method of manufacturing a chondroitin-sulfuric-acid-containing substance according to  claim 6  or  7 , wherein alkali is added at the time of said enzyme treatment.  
   
   
       9 . The chondroitin-sulfuric-acid-containing substance manufactured according to the method of claims  6 , or  7 .  
   
   
       10 . The chondroitin-sulfuric-acid-containing substance according to  claim 9 , wherein said substance is a raw material for either cosmetics or foods.