Composition to enhance HDL cholesterol and to decrease intima-media thickening in animals and humans and a method for its preparation

Abstract

A method of producing a product to correct hypercholesterolemia comprising pulping fruits of Emblica Officinalis with demineralized water to create a slurry. The slurry is treated with pectinase. The slurry is filtered to create a solution. The solution is concentrated to create a product.

1 . A method of producing a product to correct hypercholesterolemia comprising: 
 pulping fruits of Emblica Officinalis with demineralized water to create a slurry;    treating the slurry with pectinase;    filtering the slurry to create a solution; and    concentrating the solution to generate the product.    
   
   
       2 . The method of  claim 1 , wherein the product is a free flowing powder obtained by spray drying a concentrate.  
   
   
       3 . The method of  claim 1 , wherein the product is prepared without using any organic solvent and without subjecting to any chemical treatment at any stage.  
   
   
       4 . The method of  claim 1 , wherein the product does not contain any preservative or additive.  
   
   
       5 . The method of  claim 2 , wherein the powder does not contain any preservative or additive.  
   
   
       6 . A product to correct hypercholesterolemia comprising: 
 an extract of fruits of Emblica Officinalis.    
   
   
       7 . The product of  claim 6 , wherein the product is a concentrate.  
   
   
       8 . The product of  claim 7 , wherein the product is a powder.  
   
   
       9 . The product of  claim 6 , wherein the product is prepared without using any organic solvent and without subjecting to any chemical treatment at any stage.  
   
   
       10 . The product of  claim 6 , wherein the product does not contain any preservative or additive.  
   
   
       11 . The product of  claim 6 , comprising at least 10 percent by weight of emblicanin A.  
   
   
       12 . A method of reducing serum total cholesterol levels comprising administering effective doses of the product of  claim 6 .  
   
   
       13 . A method of reducing at least one of serum LDL and VLDL cholesterol concentrations comprising administering effective doses of the product of  claim 6 .  
   
   
       14 . A method of enhancing HDL cholesterol levels comprising administering effective doses of the product of  claim 6 .  
   
   
       15 . A method of reducing triglyceride to correct dyslipidemia comprising administering effective doses of the product of  claim 6 .  
   
   
       16 . A method of preventing smooth muscle cell proliferation and reducing intima-media thickening comprising administering effective doses of the product of  claim 6 .  
   
   
       17 . A method of reducing HMG CoA reductase activity comprising administering effective doses of the product of  claim 6.