Slimming cosmetic composition containing a substance inducing the production of IL-6

Abstract

This invention relates to a slimming cosmetic composition containing at least one compound inducing the production of IL-6 by the adipocytes in the form of a mixture with an NPY antagonist and/or an α 2 antagonist and with an excipient for a cosmetic preparation.

1 - 4 . (canceled)  
   
   
       5 . A slimming cosmetic composition comprising a component inducing the production of IL-6 by the adipocytes that is capable of being obtained by fermentation by the  Rhodotorula  sp strain deposited at the C.N.C.M. of Institut Pasteur under the number I 1844, or of its producing mutants, in the form of a mixture with an excipient for cosmetic preparations.  
   
   
       6 . A slimming cosmetic composition according to  claim 5 , further comprising an α 2  antagonist component and an NPY antagonist component.  
   
   
       7 . A slimming cosmetic composition according to  claim 6 , wherein the said α 2  antagonist or NPY antagonist components are chosen from nonpeptide synthetic products, extracts of cells of tissues of animal or plant origin and products obtained from fermentation by microorganisms.  
   
   
       8 . A slimming cosmetic composition according to  claim 7 , wherein the α 2  antagonist or NPY antagonist components are capable of being obtained by fermentation by microorganisms chosen from bacteria and fungi.  
   
   
       9 . A slimming cosmetic composition according to  claim 8 , wherein the α 2  antagonist component is capable of being obtained by fermentation by the  Bacillus licheniformis  strain deposited at the C.N.C.M. of Institut Pasteur under the number I 1778, or one of its producing mutants.  
   
   
       10 . A slimming cosmetic composition according to  claim 8 , wherein the NPY antagonist component is capable of being obtained by fermentation by the  Streptomyces  sp. strain deposited at the C.N.C.M. of Institut Pasteur under the number I 1132, or one of its producing mutants.  
   
   
       11 . A slimming cosmetic composition for topical application containing an NPY antagonist, an α 2  antagonist and an inducer of the production of IL-6 by the adipocytes in combination with a cosmetically acceptable excipient.  
   
   
       12 . A slimming cosmetic composition according to  claim 11 , wherein the NPY antagonist, the α 2  antagonist and the inducer of the production of IL-6 are obtained respectively by fermentation by the I 1132, 1 1778 and I 1844 strains deposited respectively at the C.N.C.M. of Institut Pasteur.  
   
   
       13 . A method for the regulation of lipolysis/lipogenesis in the skin which comprises administering a composition according to  claim 12.