US2005256174A1PendingUtilityA1

Raf kinase inhibitors

Individually held — no corporate assignee on recordPriority: May 23, 1997Filed: Jun 10, 2005Published: Nov 17, 2005
Est. expiryMay 23, 2017(expired)· nominal 20-yr term from priority
C07D 307/68A61P 35/00C07D 417/12C07D 471/04C07D 333/38C07D 207/34C07D 409/12
59
PatentIndex Score
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Claims

Abstract

Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.

Claims

exact text as granted — not AI-modified
1 .- 17 . (canceled)  
     
     
         18 . A method for the treatment of cancerous cell growth mediated by raf kinase, comprising administering a compound of the formulae:  
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         19 . A method according to  claim 18 , comprising administering a compound of the formulae  
       
         
           
           
               
               
           
         
       
     
     
         20 . A method according to  claim 18 , comprising administering a compound of the formulae  
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         21 . A method according to  claim 18 , comprising administering a compound of the formula  
       
         
           
           
               
               
           
         
       
     
     
         22 . A method according to  claim 18 , comprising administering a compound of the formula  
       
         
           
           
               
               
           
         
       
     
     
         23 . A method according to  claim 18 , comprising administering a compound of formulae  
       
         
           
           
               
               
           
         
       
     
     
         24 . A method according to  claim 18 , comprising administering a compound of formulae  
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         25 . A compound of the formulae  
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         26 . A compound according to  claim 25 , of the formulae  
       
         
           
           
               
               
           
         
       
     
     
         27 . A compound according to  claim 25 , of the formulae  
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         28 . A compound according to  claim 25 , of the formula  
       
         
           
           
               
               
           
         
       
     
     
         29 . A compound according to  claim 25 , of the formula  
       
         
           
           
               
               
           
         
       
     
     
         30 . A compound according to  claim 25 , of the formulae  
       
         
           
           
               
               
           
         
       
     
     
         31 . A compound according to  claim 25 , of the formulae

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