US2005169936A1PendingUtilityA1

Epithelial cell growth inhibitors

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Assignee: BIOTHERAPIES INCPriority: Jun 18, 1999Filed: Feb 15, 2005Published: Aug 4, 2005
Est. expiryJun 18, 2019(expired)· nominal 20-yr term from priority
Inventors:Paul R. Ervin, Jr.
C07K 14/4703A61K 38/00
42
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Claims

Abstract

Epithelial cell growth inhibitors differentially express in normal and cancerous epithelial cells. The ECGI proteins and nucleic acid sequence encoding them are useful in the diagnosis and treatment of epithelial cell cancers, for example prostate, ovarian, colon cancer, and the like.

Claims

exact text as granted — not AI-modified
1 - 10 . (canceled)  
     
     
         11 . A protein having the following characteristics: 
 i. a molecular weight of approximately 50-60 ka;    ii. produced by normal prostate, colon, or ovarian cells, but not by prostate, colon, or ovarian cancer cells; and    iii. binds antibody 7G6 (ATCC Accession No. PTA-4606).    
     
     
         12 . The protein of claim  1 , wherein said protein is produced by normal prostate cells, and is encoded by SEQ ID NO:4.  
     
     
         13 . A process for inhibiting growth of prostate, colon, or ovarian cells, comprising administering to said cells the protein of claim  1 .  
     
     
         14 . A process for inhibiting growth of prostate cells comprising administering to said cells the protein of claim  2 .

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