US2005159453A1PendingUtilityA1

Novel methods for the treatment and prevention of ileus

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Assignee: ADOLOR CORPPriority: Apr 27, 2000Filed: Dec 28, 2004Published: Jul 21, 2005
Est. expiryApr 27, 2020(expired)· nominal 20-yr term from priority
Inventors:John J. FarrarPeter J. SchiedWilliam K. SchmidtRandall L. Carpenter
A61K 31/439A61K 31/445A61K 31/451A61K 31/453A61K 31/454
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PatentIndex Score
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Claims

Abstract

Novel methods for the treatment and/or prevention of ileus. The methods may comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods include piperidine-N-alkylcarboxylates, quaternary morphinans, opium alkaloid derivatives and quaterary benzomorphans. The methods are particularly suitable for treating and/or preventing postsurgical ileus and postpartum ileus.

Claims

exact text as granted — not AI-modified
1 - 20 . (canceled)  
     
     
         21 . A method of treating or preventing ileus comprising administering to a patient an effective amount of a peripheral mu opioid antagonist compound.  
     
     
         22 - 48 . (canceled)

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