Non-particulate organic porous material having optical resolution capability and method for manufacturing same

Abstract

A non-particulate organic porous material with optical resolution capability, the non-particulate organic porous material having a continuous pore structure, which comprises macropores and mesopores, the macropores being interconnected forming mesopores with a radius of 0.01-100 μm in the interconnected parts, and optically active groups uniformly introduced therein possesses high physical stability, can be used under wide separating conditions, and has a large capacity for separating optically active substances (enantiometers).

1 . A non-particulate organic porous material having optical resolution capability, the non-particulate organic porous material having a continuous pore structure, which comprises macropores and mesopores, the macropores being interconnected forming mesopores with a radius of 0.01-100 μm in the interconnected parts, and optically active groups uniformly introduced therein.  
     
     
         2 . A non-particulate organic porous material having optical resolution capability obtained by eliminating a part or all of the optically active groups from the first non-particulate organic porous material of  claim 1 .  
     
     
         3 . The non-particulate organic porous material having optical resolution capability according to  claim 1  or  claim 2 , wherein the total pore volume of the non-particulate organic porous material is 1-50 ml/g.  
     
     
         4 . The non-particulate organic porous material having optical resolution capability according to  claim 1  or  claim 2 , wherein the amount of optically active groups introduced is 0.1 mmol/g or greater.  
     
     
         5 . The non-particulate organic porous material having optical resolution capability according to  claim 1  or  claim 2 , wherein the amount of optically active groups introduced is 0.5-500 mmol/g or greater.  
     
     
         6 . The non-particulate organic porous material having optical resolution capability according to  claim 1  or  claim 2 , wherein micropores which are non-continuous and having an average pore size of 5-800 nm are further formed in the inner wall of the continuous porous structure formed from the macropores and mesopores.  
     
     
         7 . The non-particulate organic porous material having optical resolution capability according to  claim 1  or  claim 2 , wherein the optically active groups are amino acids or their derivatives, optically active crown ethers, cyclodextrin or its derivatives, groups having asymmetrical carbon atoms, optically active naturally occurring polymers, or optically active synthetic polymers.  
     
     
         8 . The non-particulate organic porous material having optical resolution capability according to  claim 1  or  claim 2 , which is an adsorbent for separating enantiomers.  
     
     
         9 . A method for manufacturing the non-particulate organic porous material having optical resolution capability according to  claim 1 , comprising preparing a mixture of an oil-soluble monomer containing optically active groups, a surfactant, and water, stirring the mixture to prepare a water-in-oil-type emulsion, and allowing the emulsion to stand to polymerize the monomer.  
     
     
         10 . A method for manufacturing the non-particulate organic porous material having optical resolution capability according to  claim 2 , comprising preparing a mixture of an oil-soluble monomer containing optically active groups, a surfactant, and water, stirring the mixture to prepare a water-in-oil-type emulsion, allowing the emulsion to stand to polymerize the monomer, and then causing a part or all of the optically active groups to be eliminated.  
     
     
         11 . The method according to  claim 10 , wherein the optically active groups are eliminated by a method of causing the organic porous material into which the optically active groups are introduced to come in contact with trifluoroacetic acid or a method of hydrolyzing the bond of the optically active groups and the organic porous material in the presence of an acid catalyst or a base catalyst.