US2005142062A1PendingUtilityA1

Novel method of diagnosing and treating gliomas

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Priority: Dec 27, 1995Filed: Feb 15, 2005Published: Jun 30, 2005
Est. expiryDec 27, 2015(expired)· nominal 20-yr term from priority
Inventors:Harald W. SontheimerNicole Ullrich
G01N 33/57557G01N 33/5759G01N 2333/705Y10S436/813C07K 16/28C07K 2319/23A61K 38/00C07K 14/43522A61K 2039/505C07K 2319/55A61K 47/6415C07K 16/3053
51
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Claims

Abstract

The present invention provides a recombinant toxin and monoclonal antibody which specifically binds to glial-derived or meningioma-derived tumor cells. Also provided are various methods of screening for malignant gliomas and meningiomas. Further provided are methods of treating malignant gliomas, including glioblastoma multiforme and astrocytomas.

Claims

exact text as granted — not AI-modified
1 . A pharmaceutical composition, comprising a ligand which binds specifically to glial-derived or meningioma-derived tumor cells and a pharmaceutically acceptable carrier.  
     
     
         2 - 20 . (canceled)

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