US2005136032A1PendingUtilityA1
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
Priority: Jun 4, 2001Filed: Jan 7, 2005Published: Jun 23, 2005
Est. expiryJun 4, 2021(expired)· nominal 20-yr term from priority
Inventors:Nnochiri Ekwuribe
A61P 43/00A61K 2039/6093A61K 47/60A61P 5/00C07K 1/1077A61K 39/385
57
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
A non-polydispersed mixture of conjugates in which each conjugate in the mixture comprises a drug coupled to an oligomer that includes a polyalkylene glycol moiety is disclosed. The mixture may exhibit higher in vivo activity than a polydispersed mixture of similar conjugates. The mixture may be more effective at surviving an in vitro model of intestinal digestion than polydispersed mixtures of similar conjugates. The mixture may result in less inter-subject variability than polydispersed mixtures of similar conjugates.
Claims
exact text as granted — not AI-modified1 . A substantially monodispersed mixture of conjugates, each conjugate comprising a drug coupled to an oligomer that comprises a polyalkylene glycol moiety.
2 - 103 . (canceled)Join the waitlist — get patent alerts
Track US2005136032A1 — get alerts on status changes and closely related new filings.
We store only your email — no account needed. See our privacy policy.