Methods for genetic analysis

Abstract

The invention provides nucleic acid sequences which are complementary, in one embodiment, to a wide variety of murine genes. The invention provides the sequences in such a way as to make them available for a variety of analyses. As such, the invention related to diverse fields impacted by the nature of molecular interaction, including chemistry, biology, medicine, and medical diagnostics.

1 - 76 . (cancelled)  
     
     
         77 . An array comprising a plurality of nucleic acid probes wherein each probe in said plurality of nucleic acid probes consists essentially of one of the sequences listed in SEQ ID Nos. 1-127,811 and wherein said plurality of nucleic acid probes of the array comprises each of the sequences listed in SEQ ID Nos. 1-127,811.  
     
     
         78 . An array comprising 127,811 different sequence nucleic acid probes attached to a solid support at known locations, wherein each different sequence nucleic acid probe is 20 to 30 nucleotides and is completely complementary to a region of the mouse genome.  
     
     
         79 . A method of monitoring the expression of a plurality of mouse genes in a first nucleic acid sample obtained from a mouse sample, said method comprising: 
 obtaining a second nucleic acid sample by amplifying a plurality of nucleic acids in said first sample;    hybridizing said second nucleic acid sample to the array of  claim 78  to obtain a hybridization pattern; and    analyzing said hybridization pattern to obtain a measurement of the expression of a plurality of mouse genes.