Methods for screening for transdominant effector peptides and RNA molecules

Abstract

Methods and compositions for screening for transdominant effector peptides and RNA molecules selected inside living cells from randomized pools are provided.

1 . A method for screening for a transdominant bioactive agent capable of altering the phenotype of a cell, said method comprising the steps: 
 a) introducing a molecular library of randomized candidate nucleic acids into a plurality of cells, wherein which of said nucleic acids comprises a different nucleotide sequence;    b) screening said plurality of cells for a cell exhibiting an altered phenotype, wherein said altered phenotype is due to the presence of a transdominant bioactive agent.    
     
     
         2 .- 27 . (Cancelled)