Porous particles loaded with cosmetically or pharmaceutically active compounds

Abstract

The present invention relates to individualized porous particles, characterized in that they have a volume-average diameter of less than or equal to 10 μm and a specific surface area of greater than or equal to 1 m 2 /g, and in that they comprise at least one cosmetically or pharmaceutically active compound at least present inside said particles.

1 . Individualized porous particles, characterized in that they have a volume-average diameter of less than or equal to 10 μm and a specific surface area of greater than or equal to 1 m 2 /g, and in that they comprise at least one cosmetically or pharmaceutically active compound at least present inside said particles.  
     
     
         2 . Particles according to  claim 1 , characterized in that they have a specific surface area ranging from 2.5 to 1000 m 2 /g, and in particular from 3 to 750 m 2 /g.  
     
     
         3 . Particles according to either one of the preceding claims, characterized in that they have a mass by volume of greater than or equal to 0.15 g/cm 3 , and in particular ranging from 0.2 to 5 g/cm 3 .  
     
     
         4 . Particles according to any one of the preceding claims, characterized in that they have a volume-average diameter of greater than or equal to 0.1 μm, and in particular ranging from 0.5 to 8 μm.  
     
     
         5 . Particles according to any one of the preceding claims, characterized in that they have a polydispersity index ranging from 1 to 4, and in particular less than or equal to 3.  
     
     
         6 . Particles according to any one of the preceding claims, characterized in that they are provided in the form of a powder.  
     
     
         7 . Particles according to any one of the preceding claims, characterized in that they derive from organic porous particles.  
     
     
         8 . Particles according to  claim 7 , characterized in that said organic porous particles are chosen from particles of Nylon 6, Nylon 6-6, Nylon 12 and Nylon 6-12 and particles of poly(methyl methacrylate).  
     
     
         9 . Particles according to any one of  claims 1  to  6 , characterized in that they derive from inorganic porous particles.  
     
     
         10 . Particles according to  claim 9 , characterized in that said inorganic porous particles are chosen from particles of silica, of alumina-silica, of hydroxyapatite, of titanium dioxide or of mixtures thereof.  
     
     
         11 . Particles according to any one of the preceding claims, characterized in that they derive from porous particles made of an organic and inorganic composite material.  
     
     
         12 . Particles according to any one of the preceding claims, characterized in that the ratio by weight of the active compound(s) to the porous particles not loaded with active compound(s) is from 1/1000 to 10/1, and in particular from 1/100 to 1/1.  
     
     
         13 . Particles according to any one of the preceding claims, characterized in that they comprise at least one cosmetically or pharmaceutically active compound chosen from antibacterial agents, antifungal agents, sebum regulators, sebum stimulators, keratolytic agents, agents for treating acne, antibiotics, hair loss inhibitors/hair growth stimulators, agents which inhibit the growth of head hair or of body hair, anti-dandruff agents, antioxidants, astringents, pore-reducing agents, antiperspirant agents, vitamins, anti-inflammatory agents, and mixtures thereof.  
     
     
         14 . Cosmetic or pharmaceutical composition, characterized in that it comprises particles as defined in any one of  claims 1  to  13 .  
     
     
         15 . Cosmetic or pharmaceutical composition according to  claim 14 , characterized in that the proportion by weight of said particles relative to the total weight of said composition is from 0.1 to 50%, and in particular from 0.2 to 20%.  
     
     
         16 . Cosmetic or pharmaceutical composition according to either one of claims  14  and  15 , characterized in that it is provided in the form of a lotion, an O/W emulsion, a W/O emulsion, or an aqueous or aqueous-alcoholic gel, or in anhydrous form, such as a stick, a spray or a compact or free powder.