Implantable device and use therefor

Abstract

Disclosed is an implantable device for delivering a preselected molecule, for example, a hormone, into a mammal's systemic circulation. The device comprises a blood permeable element that can be anchored to an inner wall of an intact blood vessel. The device also comprises a capsule that is held in place within the blood vessel by the anchored blood permeable element. The capsule encloses viable cells which produce and secrete the pre-selected molecule into blood passing the capsule. The invention also provides a minimally invasive method for percutaneously introducing into a preselected blood vessel the device of the invention.

1 . A device for delivering a pre-selected molecule into systemic circulation, the device comprising: 
 (a) a blood permeable element anchored to an inner wall of an intact blood vessel which permits blood in the vessel to pass therethrough; and    (b) a capsule in contact with the element within the vessel and having disposed therein viable cells which produce and secrete the pre-selected molecule into blood passing the capsule.    
     
     
         2 - 46 . (Canceled)