US2005008856A1PendingUtilityA1
Medical device having electrostatic coating with chemotherapeutic agents
Priority: Jun 29, 2000Filed: Aug 12, 2004Published: Jan 13, 2005
Est. expiryJun 29, 2020(expired)· nominal 20-yr term from priority
Inventors:Vipul Dave
D06M 15/09A61L 17/145A61C 15/041D06M 15/507D06M 15/53B29B 15/12D06M 23/08D06M 10/10B05D 2256/00A61L 2300/416A61L 27/54Y10T428/2913D06M 15/693A61L 2300/606B05D 1/06D06M 15/227A61L 31/16
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Claims
Abstract
A medical device is made of a substrate; and at least one coating electrostatically coated on the substrate or at least one coating electrostatically impregnated with the substrate. The medical device is a device such as a stent, catheter or suture. The medical device is made of a material such as a ceramic, metal alloy or polymer. At least one chemotherapeutic agent and/or at least one active ingredient can be used with the at least one coating.
Claims
exact text as granted — not AI-modified1 - 14 . (Cancelled)
15 . A medical device comprising:
a substrate; and at least one coating electrostatically coated on the substrate.
16 . The medical device according to claim 15 , wherein the substrate is made of a material from the group consisting of ceramics, metal alloys or polymers.
17 . The medical device according claim 16 , wherein the medical device is from the group consisting of stents, catheters or sutures.
18 . The medical device according to claim 17 , further comprising at least one chemotherapeutic agent with the at least one coating.
19 . The medical device according to claim 17 , further comprising at least one active ingredient with the at least one coating.
20 . The medical device according to claim 15 further comprising at least one chemotherapeutic agent with the at least one coating.
21 . The medical device according to claim 15 , further comprising at least one active ingredient with the at least one coating.
22 . The medical device according to claim 15 , wherein the at least one coating comprises a first coating and a second coating.
23 . The medical device according to claim 22 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
24 . The medical device according to claim 23 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
25 . The medical device according to claim 17 , wherein the at least one coating comprises a first coating and a second coating.
26 . The medical device according to claim 25 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
27 . The medical device according to claim 26 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
28 . The medical device according to claim 18 , wherein the at least one coating comprises a first coating and a second coating.
29 . The medical device according to claim 28 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
30 . The medical device according to claim 29 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
31 . The medical device according to claim 19 , wherein the at least one coating comprises a first coating and a second coating.
32 . The medical device according to claim 31 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
33 . The medical device according to claim 32 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
34 . A medical device comprising:
a substrate; and at least one coating electrostatically impregnated with the substrate.
35 . The medical device according to claim 34 , wherein the substrate is made of a material from the group consisting of ceramics, metal alloys or polymers.
36 . The medical device according claim 35 , wherein the medical device is from the group consisting of stents, catheters or sutures.
37 . The medical device according to claim 36 , further comprising at least one chemotherapeutic agent with the at least one coating
38 . The medical device according to claim 37 , further comprising at least one active ingredient with the at least one coating.
39 . The medical device according to claim 34 , further comprising at least one chemotherapeutic agent with the at least one coating.
40 . The medical device according to claim 34 , further comprising at least one active ingredient with the at least on coating.
41 . The medical device according to claim 34 , wherein the at least one coating comprises a first coating and a second coating.
42 . The medical device according to claim 41 , wherein the first coating is from group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
43 . The medical device according to claim 42 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
44 . The medical device according to claim 36 wherein the at least one coating comprises a first coating and a second coating.
45 . The medical device according to claim 44 , wherein the first coating is from the group of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
46 . The medical device according to claim 45 , wherein the second coating from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
47 . The medical device according to claim 37 , wherein the at least one coating comprises a first coating and a second coating.
48 . The medical device according to claim 47 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
49 . The medical device according to claim 48 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
50 . The medical device according to claim 38 , wherein the at least on coating comprises a first coating and a second coating.
51 . The medical device according to claim 50 , herein the first coating is from the group poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
52 . The medical device according to claim 51 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
53 . A stent comprising:
a substrate; and at least one coating electrostatically coated on the substrate.
54 . The stent according to claim 53 , wherein the substrate is made from a ceramic material.
55 . The stent according to claim 53 , wherein the substrate is made from a metal alloy.
56 . The stent according to claim 53 , wherein the substrate is made from a polymer.
57 . The stent according to claim 53 , further comprising at least one chemotherapeutic agent with the at least one coating.
58 . The stent according to claim 54 , further comprising at least one chemotherapeutic agent with the at least one coating.
59 . The stent according to claim 55 , further comprising at least one chemotherapeutic agent with the at least one coating.
60 . The stent according to claim 56 , further comprising at least one chemotherapeutic agent with the at least one coating.
61 . The stent according to claim 53 , further comprising at least one active ingredient with the at least one coating.
62 . The stent according to claim 54 , further comprising at least one active ingredient with the at least one coating.
63 . The stent according to claim 55 , further comprising at least one active ingredient with the at least one coating.
64 . The stent according to claim 56 , further comprising at least one active ingredient with the at least one coating.
65 . The stent according to claim 53 , wherein the at least one coating comprises a first coating and a second coating.
66 . The stent according to claim 65 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
67 . The stent according to claim 66 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
68 . The stent according to claim 65 , further comprising at least one chemotherapeutic agent with the at least one coating.
69 . The stent according to claim 65 , further comprising at least one active ingredient with the at least one coating.
70 . A stent comprising:
a substrate; and at least one coating electrostatically impregnated with the substrate.
71 . The stent according to claim 70 , wherein the substrate is made from a ceramic material.
72 . The stent according to claim 70 , wherein the substrate is made from a metal alloy.
73 . The stent according to claim 70 , wherein the substrate is made from a polymer.
74 . The stent according to claim 70 , further comprising at least one chemotherapeutic agent with the at least one coating.
75 . The stent according to claim 71 , further comprising at least one chemotherapeutic agent with the at least one coating.
76 . The stent according to claim 72 , further comprising at least one chemotherapeutic agent with the at least one coating.
77 . The stent according to claim 73 , further comprising at least one chemotherapeutic agent with the at least one coating.
78 . The stent according to claim 70 , further comprising at least one active ingredient with the at least one coating.
79 . The stent according to claim 71 , further comprising at least one active ingredient with the at least one coating.
80 . The stent according to claim 72 , further comprising at least one active ingredient with the at least one coating.
81 . The stent according to claim 73 , further comprising at least one active ingredient with the at least one coating.
82 . The stent according to claim 70 , wherein the at least one coating comprises a first coating and a second coating.
83 . The stent according to claim 82 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
84 . The stent according to claim 83 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
85 . The stent according to claim 82 , further comprising at least one chemotherapeutic agent with the at least one coating.
86 . The stent according to claim 82 , further comprising at least on active ingredient with the at least one coating.
87 . A stent comprising:
a substrate made from a ceramic material; at least one coating electrostatically coated on the substrate; and at least one chemotherapeutic agent with the at least one coating.
88 . The stent according to claim 87 , wherein the at least one coating comprises a first coating and a second coating.
89 . The stent according to claim 88 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
90 . The stent according to claim 89 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
91 . A stent comprising:
a substrate made from a ceramic material; at least one coating electrostatically impregnated with the substrate; and at least one chemotherapeutic agent with the at least one coating.
92 . The stent according to claim 91 , wherein the at least one coating comprises a first coating and a second coating.
93 . The stent according to claim 92 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
94 . The stent according to claim 93 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
95 . A stent comprising:
a substrate made from a ceramic material; at least one coating electrostatically coated on the substrate; and at least one active ingredient with the at least one coating.
96 . The stent according to claim 95 , wherein the at least one coating comprises a first coating and a second coating.
97 . The stent according to claim 96 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
98 . The stent according to claim 97 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
99 . A stent compising:
a substrate made from a ceramic material; at least one coating electrostatically impregnated with the substrate; and at least one active ingredient with the at least one coating.
100 . The stent according to claim 99 , wherein the at least one coating comprises a first coating and a second coating.
101 . The stent according to claim 100 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
102 . The stent according to claim 101 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
103 . A stent comprising:
a substrate made from a metal alloy; at least one coating electrostatically coated on the substrate; and at least one chemotherapeutic agent with the at least one coating.
104 . The stent according to claim 103 , wherein the at least one coating comprises a first coating and a second coating.
105 . The stent according to claim 104 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
106 . The stent according to claim 105 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
107 . A stent comprising:
a substrate made from a metal alloy; at least one coating electrostatically impregnated with the substrate; and at least one chemotherapeutic agent with the at least one coating.
108 . The stent according to claim 107 , wherein the at least one coating comprises a first coating and a second coating.
109 . The stent according to claim 108 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
110 . The stent according to claim 109 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
111 . A stent comprising:
a substrate made from a metal alloy; at least one coating electrostatically coated on the substrate; and at least one active ingredient with the at least one coating.
112 . The stent according to claim 111 , wherein the at least one coating comprises a first coating and a second coating.
113 . The stent according to claim 112 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
114 . The stent according to claim 113 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
115 . A stent comprising:
a substrate made from a metal alloy at least one coating electrostatically impregnated with the substrate; at least one active ingredient with the at least one coating.
116 . The stent according to claim 115 , wherein the at least one coating comprises a first coating and a second coating.
117 . The stent according to claim 116 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
118 . The stent according to claim 117 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
119 . A stent comprising:
a substrate made from a polymer; at least one coating electrostatically coated on the substrate; and at least one chemotherapeutic agent with the at least one coating.
120 . The stent according to claim 119 , wherein the at least one coating comprises a first coating and a second coating.
121 . The stent according to claim 120 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
122 . The stent according to claim 121 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
123 . A stent comprising:
a substrate made from a polymer; at least one coating electrostatically impregnated with the substrate; and at least one chemotherapeutic agent with the at least one coating.
124 . The stent according to claim 123 , wherein the at least one coating comprises a first coating and a second coating.
125 . The stent according to claim 124 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
126 . The stent according to claim 125 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
127 . A stent comprising:
a substrate made from a polymer; at least one coating electrostatically coated on the substrate; at least one active ingredient with the at least one coating.
128 . The stent according to claim 127 , wherein the at least one coating comprises a first coating and a second coating.
129 . The stent according to claim 128 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
130 . The stent according to claim 129 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
131 . A stent comprising:
a substrate made from a polymer; at least one coating electrostatically impregnated with the substrate; and at least one active ingredient with the at least one coating.
132 . The stent according to claim 131 , wherein the at least one coating comprises a first coating and a second coating.
133 . The stent according to claim 132 , wherein the first coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.
134 . The stent according to claim 133 , wherein the second coating is from the group consisting of poly(ethylene oxide); poly(ethylene glycol); hydroxyethyl cellulose; hydroxypropyl cellulose; polyethylene; waxes such as microcrystalline wax; polyvinylidene fluoride and polycaprolactone.Join the waitlist — get patent alerts
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