US2005006255A1PendingUtilityA1

Contact lens packages containing additives

Priority: Dec 23, 2002Filed: Dec 9, 2003Published: Jan 13, 2005
Est. expiryDec 23, 2022(expired)· nominal 20-yr term from priority
B65B 25/008B65B 25/00A45C 11/046A61L 12/08A61L 12/086A45C 11/04A61J 1/00B65B 55/22A45C 11/00A45C 11/005
46
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Claims

Abstract

A package having an additive that does not adhere to a medical device enclosed therein.

Claims

exact text as granted — not AI-modified
1 . A package for storing medical devices in a solution comprising a molded base wherein the molded base comprises an additive, provided that the medical device is not a contact lens consisting of acqualfilcon A coated with polyHema.  
     
     
         2 . The package of  claim 1  wherein the additive is selected from the group consisting of succinic acid, glycerol monostearate, PVP, and PVP/maleic anhydride.  
     
     
         3 . The package of  claim 1  wherein the additive is glycerol monostearate.  
     
     
         4 . The package of  claim 3  wherein glycerol monostearate is present at a concentration of greater than about 0.5 weight percent to about 5 weight percent.  
     
     
         5 . The package of  claim 3  wherein glycerol monostearate is present at a concentration of about 2 percent.  
     
     
         6 . The package of  claim 1  wherein the additive is PVP KD90.  
     
     
         7 . The package of  claim 6  wherein the PVP concentration is about 1% to about 5%.  
     
     
         8 . The package of  claim 6  wherein the PVP concentration is about 1.0%.  
     
     
         9 . The package of  claim 1  wherein the additive is PVP KD90/maleic anhydride.  
     
     
         10 . The package of  claim 9  wherein the PVP KD90/maleic anhydride concentration is about 1/1% to about 5/5%.  
     
     
         11 . The package of  claim 1  wherein the medical device is a contact lens which comprises balafilcon A, lotrafilcon A, galyfilcon, senofilcon, or lenses disclosed in U.S. patent application Ser. No. 60/318,536, entitled Biomedical Devices Containing Internal wetting Agents,” filed on Sep. 10, 2001 and its non-provisional counterpart of the same title, filed on Sep. 6, 2002.  
     
     
         12 . The package of  claim 11  wherein the contact lens comprises Simma 2 and mPDMS.  
     
     
         13 . The package of  claim 11  wherein the contact lens comprises Simma 2  
     
     
         14 . The package of  claim 1  wherein the molded base comprises polypropylene.  
     
     
         15 . The package of  claim 1  further comprising a cavity formed in said molded base wherein said cavity comprises an inner surface, wherein said inner surface has an average roughness of about 0.5 μm to about 20 μm.  
     
     
         16 . The package of  claim 15  wherein the inner surface has an average roughness of about 1.8 μm to about 4.5 μm.  
     
     
         17 . The package of  claim 15  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm  
     
     
         18 . The package of  claim 15  wherein the inner surface has an average roughness of about 0.5 μm to about 0.8 μm.  
     
     
         19 . The package of  claim 1  further comprising a cavity formed in said molded base wherein said cavity comprises an inner surface, wherein said inner surface has an average roughness of about 0.5 μm to about 20 μm and the additive is glycerol monostearate or PVP.  
     
     
         20 . The package of  claim 19  wherein the average roughness of the inner surface is about 0.5 μm to about 0.8 μm and the concentration of PVP is about 1%.  
     
     
         21 . The package of  claim 19  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm and the concentration of PVP is about 1%.  
     
     
         22 . The package of  claim 1  further comprising a cavity formed in said molded base wherein said cavity comprises an inner surface, wherein said inner surface has an average roughness of about 0.5 μm to about 20 μm and the additive is maleic anhydride or PVP/maleic anhydride.  
     
     
         23 . The package of  claim 22  wherein the average roughness of the inner surface is about 0.5 μm to about 0.8 μm and the concentration of PVP/maleic anhydride is about 1%.  
     
     
         24 . The package of  claim 22  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm and the concentration of PVP/maleic anhydride is about 1%.  
     
     
         25 . The package of  claim 22  wherein the average roughness of the inner surface is about 0.5 μm to about 0.8 μm and the concentration of maleic anhydride is about 1%.  
     
     
         26 . The package of  claim 22  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm and the concentration of maleic anhydride is about 1%.  
     
     
         27 . A method of reducing the adherence of a medical device to its packaging, comprising storing said medical device in a solution in a package comprising a molded base wherein said molded base comprises an additive, provided that the medical device is not a contact lens consisting of acqualfilcon A coated with polyHema.  
     
     
         28 . The method of  claim 27  wherein additive is selected from the group consisting of succinic acid, glycerol monostearate, and PVP.  
     
     
         29 . The method of  claim 27  wherein the additive is glycerol monostearate.  
     
     
         30 . The method of  claim 27  wherein glycerol monostearate is present at a concentration of greater than about 0.25 weight percent to about 5 weight percent.  
     
     
         31 . The method of  claim 27  wherein glycerol monostearate is present at a concentration of about 2 percent.  
     
     
         32 . The method of  claim 27  wherein the additive is PVP KD90.  
     
     
         33 . The method of  claim 27  wherein the PVP is present at about 1% to about 5%.  
     
     
         34 . The method of  claim 27  wherein the contact lens comprises balafilcon A, lotrafilcon A, or lenses disclosed in U.S. patent application Ser. No. 60/318,536, entitled Biomedical Devices Containing Internal wetting Agents,” filed on Sep. 10, 2001 and its non-provisional counterpart of the same title, filed on Sep. 6, 2002.  
     
     
         35 . The method of  claim 27  wherein the contact lens comprises Simma 2  
     
     
         36 . The method of  claim 27  wherein the molded base comprises polypropylene.  
     
     
         37 . The method of  claim 27  further comprising a cavity formed in said molded base wherein said cavity comprises an inner surface, wherein said inner surface has an average roughness of about 0.5 μm to about 20 μm and the additive is glycerol monostearate or PVP.  
     
     
         38 . The method of  claim 37  wherein the average roughness of the inner surface is about 0.5 μm to about 0.8 μm and the concentration of PVP is about 1%.  
     
     
         39 . The method of  claim 37  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm and the concentration of PVP is about 1%.  
     
     
         40 . The method of  claim 27  further comprising a cavity formed in said molded base wherein said cavity comprises an inner surface, wherein said inner surface has an average roughness of about 0.5 μm to about 20 μm and the additive is maleic anhydride or PVP/maleic anhydride.  
     
     
         41 . The method of  claim 40  wherein the average roughness of the inner surface is about 0.5 μm to about 0.8 μm and the concentration of PVP/maleic anhydride is about 1%.  
     
     
         42 . The method of  claim 40  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm and the concentration of PVP/maleic anhydride is about 1%.  
     
     
         43 . The method of  claim 40  wherein the average roughness of the inner surface is about 0.5 μm to about 0.8 μm and the concentration of maleic anhydride is about 1%.  
     
     
         44 . The method of  claim 40  wherein the inner surface has an average roughness of about 1.9 μm to about 2.1 μm and the concentration of maleic anhydride is about 1%.  
     
     
         45 . A method of hydrating a contact lens comprising, consisting essentially of, or consisting of hydrating said lens in a molded base wherein said molded base comprises an additive.  
     
     
         46 . The method of  claim 45  wherein the additive is selected from the group consisting of succinic acid, glycerol monostearate, PVP, and PVP/maleic anhydride.  
     
     
         47 . The method of  claim 46  wherein the additives are present at a concentration of greater than about 0.25 weight percent to about 5 weight percent.  
     
     
         48 . The method of  claim 45  wherein the molded base further comprises a cavity formed in said molded base wherein said cavity comprises an inner surface, wherein said inner surface has an average roughness of about 0.5 μm to about 20 μm and the additive is maleic anhydride or PVP/maleic anhydride.

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