US2004266995A1PendingUtilityA1
Fibrinogenolytic proteases with thrombolytic and antihypertensive activities from Taiwan habu: medical application and novel process of expression and production
Est. expiryAug 24, 2021(expired)· nominal 20-yr term from priority
Inventors:Shyh-Horng Chiou
C12N 9/6418A61K 38/00C07K 2319/00Y10S530/856
41
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Claims
Abstract
The present invention provides a process of producing highly purified proteases. The invention further provides the use of such purified proteases in treating cardiovascular disorders, including hypertension, stroke and thrombosis.
Claims
exact text as granted — not AI-modified1 - 7 . Cancelled
8 . A vector for expressing a protease capable of removing said proteases from an expression product through an autocatalvtic process comprising the cleavage sequence selected from the group comprising SEQ ID 2 to 6.
9 . The vector according to claim 8 wherein the SEQ ID is 2.
10 . The vector according to claim 8 wherein the SEQ ID is 3.
11 . The vector according to claim 8 wherein the SEQ ID is 4.
12 . The vector according to claim 8 wherein the SEQ ID is 5.
13 . The vector according to claim 8 wherein the SEQ ID is 6.
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