Therapeutic composition containing at least diflomotecan and capecitabine

Abstract

The method of treating cancer by administering to a patient in need thereof a synergistic effective amount of a composition comprising at least a first component of diflomotecan and a second component of capecitabine.

1 . A method of treating cancer, comprising administering to a patient in need thereof a synergistic effective amount of at least a first component consisting of diflomotecan, and a second component consisting of capecitabine sufficient to treat cancer.  
     
     
         2 . The method of  claim 1 , wherein diflomotecan and capecitabine are administered simultaneously.  
     
     
         3 . The method of  claim 1 , wherein diflomotecan and capecitabine are administered separately.  
     
     
         4 . The method of  claim 3 , wherein diflomotecan is administered first.  
     
     
         5 . The method of  claim 3 , wherein capecitabine is administered first.  
     
     
         6 . The method of  claim 1 , wherein diflomotecan and capecitabine e are administered sequenced over time.  
     
     
         7 . The method of  claim 1 , wherein the cancer is selected from the group consisting of breast cancer, colon cancer and rectum cancer.  
     
     
         8 - 9 . (cancelled)  
     
     
         10 . A composition for treating cancer comprising a synergistic amount of a first component consisting of diflomotecan as active ingredient, and a second component consisting of capecitabine as active ingredient.  
     
     
         11 - 13 . (cancelled)  
     
     
         14 . A composition of  claim 10 , wherein the cancer is breast cancer, colon cancer or rectum cancer.