Meconium aspiration syndrome treatments

Abstract

The present invention provides a method of treating meconium aspiration syndrome, said method comprising administering to a subject in need of treatment a therapeutically effective amount of albumin. A further aspect of the invention relates to the use of albumin in the preparation of a medicament for treating meconium aspiration syndrome, and a pharmaceutical composition comprising albumin admixed with a pharmaceutically acceptable carrier, diluent or excipient.

What is claimed is:  
     
         1 . A pharmaceutical composition comprising albumin and one or more bile acid blockers admixed with a pharmaceutically acceptable carrier, diluent or excipient.  
     
     
         2 . A pharmaceutical composition according to  claim 1  wherein said composition further comprises one or more surfactants.  
     
     
         3 . A pharmaceutical composition according to  claim 1  wherein the albumin is selected from the group consisting of serum albumin, plasma albumin, ovalbumin, lactalbumin, and soybean albumin.  
     
     
         4 . A pharmaceutical composition according to  claim 3  wherein the albumin is serum albumin.  
     
     
         5 . A pharmaceutical composition according to  claim 4  wherein the albumin is bovine serum albumin.  
     
     
         6 . A pharmaceutical composition according to  claim 1  wherein the bile acid blocker is selected from the group consisting of cholestyramin, antibodies against bile acids, and mixtures thereof.  
     
     
         7 . A pharmaceutical composition comprising: 
 albumin selected from the group consisting of serum albumin, plasma albumin, ovalbumin, lactalbumin, and soybean albumin;    one or more bile acid blockers selected from the group consisting of cholestyramin, antibodies against bile acids, and mixtures thereof;    and a pharmaceutically acceptable carrier, diluent or excipient.    
     
     
         8 . A pharmaceutical composition according to  claim 7  wherein said composition further comprises one or more surfactants.  
     
     
         9 . A pharmaceutical composition according to  claim 8  wherein the albumin is serum albumin.  
     
     
         10 . A pharmaceutical composition according to  claim 9  wherein the albumin is bovine serum albumin.