US2004209870A1PendingUtilityA1
Novel 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole compounds

Priority: Mar 14, 2000Filed: Jan 20, 2004Published: Oct 21, 2004
Est. expiryMar 14, 2020(expired)· nominal 20-yr term from priority
Inventors:Michael Ennis Robert Louis Hoffman Nabil Ghazal Rebecca Olson
A61P 37/04A61P 9/12A61P 39/02A61P 43/00A61P 25/02A61P 25/24A61P 3/04A61P 25/28A61P 25/30A61P 25/14A61P 25/20A61P 25/18A61P 25/00A61P 25/22A61P 25/06A61P 25/04A61P 15/10A61P 15/08A61P 1/08A61P 21/00C07D 209/18C07D 487/04
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Claims
Abstract

A compound of formula I: where a is a single bond or double bond, and where R1a, R1b, R2a and R2b are each independently (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6; (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or (c) linear or branched C 1 -C 8 alkyl, linear or branched C 2 -C 8 alkenyl, linear or branched C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkenyl, or C 3 -C 8 cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where R3 is (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) n N(R6)C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 and Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or (b) linear or branched C 1 -C 8 alkyl, linear or branched C 2 -C 8 alkenyl, linear or branched C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkenyl, or C 3 -C 8 cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where R4, R5 and R6 are each independently (a) H, linear or branched C 1 -C 8 alkyl, linear or branched C 2 -C 8 alkenyl, linear or branched C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkenyl, or C 3 -C 8 cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11 or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; and where R7, R8, and R9 are each independently (a) H, linear or branched C 1 -C 8 alkyl, linear or branched C 2 -C 8 alkenyl, linear or branched C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkenyl, or C 3 -C 8 cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where R10, R11 and R12 are each independently H, linear or branched C 1 -C 8 alkyl, linear or branched C 2 -C 8 alkenyl, linear or branched C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkenyl, or C 3 -C 8 cycloalkynyl; or a stereoisomer or pharmaceutically acceptable salt thereof.
Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A compound of formula I:  
       
         
           
           
               
               
           
         
       
       where a is a single bond or double bond, and where 
 R1a, R1b, R2a and R2b are each independently 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6;  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (c) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where  
 
 R3 is 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) n N(R6)C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, R7; or  
 (b) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where  
 
 R4, R5 and R6 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or  
 (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; and where  
 
 R7, R8, and R9 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where  
 
 R10, R11 and R12 are each independently H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl;  
 or a stereoisomer or pharmaceutically acceptable salt thereof.  
 
     
     
         2 . The compound of  claim 1  wherein R1a, R1b, R2a, R2b and R4 are H and R3 is selected from either H,—C(O)C(O)XAr, —CH 2 C(O)XAr or —C(O)CH 2 XAr.  
     
     
         3 . The compound of  claim 1  which is selected from the group consisting of: 
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 8-bromo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carbaldehyde  
 2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 2,2,2-trifluoro-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 11-methyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 11-chloro-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carbonitrile  
 8-bromo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carbaldehyde  
 1-(8-bromo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-2,2,2-trifluoro-1-ethanone  
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carboxamide  
 1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone hydrochloride  
 3-methyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-ethyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 10-methoxy-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 ethyl 2-(3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-2-oxoacetate  
 3-propyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indole hydrochloride  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanamine  
 2-(3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanol  
 3-benzyl-11-(2-phenoxyethyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-(2-phenoxyethyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-fluorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
   3 -benzyl-11-[2-(8-quinolinyloxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanol  
 3-benzyl-11-[2-(2-methoxy-4-methylphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-fluoro-6-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 11-[2-(2-fluorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-methoxy-4-methylphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-fluoro-6-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-chlorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(4-bromo-2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N-benzyl-2-(3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanamine  
 11-[2-(2-chlorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(4-bromo-2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-phenoxy-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 N-(4-methoxyphenyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 4-methoxy-N-[2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)ethyl]aniline dihydrochloride  
 2-hydroxy-N-(4-methoxyphenyl)-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 2-(2-methoxyphenoxy)-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 2-(4-bromo-2-methoxyphenoxy)-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 N-(4-methoxyphenyl)-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 2-(4-methoxyanilino)-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone dihydrochloride  
 N-(2,4-difluorophenyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 N-(3-chloro-4-methoxyphenyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 2-oxo-N-phenyl-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 N-(2-naphthyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 N-(2,4-difluorophenyl)-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 8-phenyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-butylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,5-trimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,5-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropyl-2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-pyridinyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-furyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzenethiol  
 8-(2,3-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 8-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-naphthyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 N-[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]acetamide  
 8-(2,3-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-5-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-3-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,6-tetrafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-ethoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-isopropoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-ethyl-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 8-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 8-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 8-(2-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzoate  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-methyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-methyl-3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 [3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[3-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzamide  
 8-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-butylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,5-trimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,5-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropyl-2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-difluorophenyl)-2,3,4,5,11,1a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-pyridinyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-furyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzenethiol  
 8-(2,3-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 8-[3-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-naphthyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 N-[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]acetamide  
 8-(2,3-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-5-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-3-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-6-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,6-tetrafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-ethoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-isopropoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-ethyl-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 8-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 8-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-benzyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 8-(2-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzoate  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-methyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-methyl-3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 [3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[3-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzamide  
 7-phenyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-butylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,5-trimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,5-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropyl-2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-pyridinyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-furyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzenethiol  
 7-(2,3-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 7-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-naphthyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 N-[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]acetamide  
 7-(2,3-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-5-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-3-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,6-tetrafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-ethoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-isopropoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-ethyl-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 7-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 7-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 7-(2-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzoate  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-methyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-methyl-3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 [3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[3-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzamide  
 7-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-butylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,5-trimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,5-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropyl-2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-pyridinyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-furyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzenethiol  
 7-(2,3-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 7-[3-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-naphthyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 N-[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]acetamide  
 7-(2,3-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-5-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-3-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-6-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,6-tetrafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-ethoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-isopropoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-ethyl-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 7-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 7-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-4-methoxyphenyl)-2,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-benzyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 7-(2-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzoate  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-methyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-methyl-3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 [3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[3-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzamide  
 9-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-butylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,5-trimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,5-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropyl-2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-pyridinyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-furyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzenethiol  
 9-(2,3-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 9-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-naphthyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 N-[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]acetamide  
 9-(2,3-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-5-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-3-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,6-tetrafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-ethoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-isopropoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-ethyl-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 9-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 9-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a ]indole  
 9-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 9-(2-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzoate  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-methyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-methyl-3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 [3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[3-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzamide  
 9-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-butylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,5-trimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,5-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropyl-2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-pyridinyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-furyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzenethiol  
 9-(2,3-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 9-[3-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-naphthyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a ]indole  
 1-[4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 N-[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]acetamide  
 9-(2,3-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-5-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-3-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-6-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,6-tetrafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethoxy)phenyl]-2,3,4,5,11,111a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-ethoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-isopropoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-ethyl-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 9-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 9-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-benzyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 9-(2-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzoate  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-methyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-methyl-3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 [3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[3-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile, and  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzamide.  
 
     
     
         4 . The compound of  claim 1  in native form, acid salt form or base salt form.  
     
     
         5 . A compound of formula I:  
       
         
           
           
               
               
           
         
       
       where a is a single bond or double bond, and where 
 R1a, R1b, R2a and R2b are each independently 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6;  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (c) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where  
 
 R3 is 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) 6 )C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 and Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (b) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where  
 
 R4, R5 and R6 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11 or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or  
 (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, C 2 R7, COR7, or R7, and where  
 
 R7, R8, and R9 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where  
 
 R10, R11 and R12 are each independently H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl;  
 or a stereoisomer or pharmaceutically acceptable salt thereof.  
 
     
     
         6 . The composition of  claim 5  wherein R1a, R1b, R2a, R2b and R4 are H and R3 is selected from either H,—C(O)C(O)XAr, —CH 2 C(O)XAr or —C(O)CH 2 XAr.  
     
     
         7 . The composition of  claim 5  wherein the compound of formula I is selected from the group consisting of: 
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 8-bromo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carbaldehyde  
 2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-1-yl)acetamide  
 2,2,2-trifluoro-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 11-methyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 11-chloro-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carbonitrile  
 8-bromo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carbaldehyde  
 1-(8-bromo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-2,2,2-trifluoro-1-ethanone  
 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole-11-carboxamide  
 1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone hydrochloride  
 3-methyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-ethyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 10-methoxy-2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indole hydrochloride  
 ethyl 2-(3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-2-oxoacetate  
 3-propyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanamine  
 2-(3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanol  
 3-benzyl-11-(2-phenoxyethyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-(2-phenoxyethyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-fluorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(8-quinolinyloxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanol  
 3-benzyl-11-[2-(2-methoxy-4-methylphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-fluoro-6-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole hydrochloride  
 11-[2-(2-fluorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-methoxy-4-methylphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(2-fluoro-6-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(2-chlorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-benzyl-11-[2-(4-bromo-2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N-benzyl-2-(3-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanamine  
 11-[2-(2-chlorophenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 11-[2-(4-bromo-2-methoxyphenoxy)ethyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-phenoxy-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 N-(4-methoxyphenyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 4-methoxy-N-[2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)ethyl]aniline dihydrochloride  
 2-hydroxy-N-(4-methoxyphenyl)-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 2-(2-methoxyphenoxy)-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 2-(4-bromo-2-methoxyphenoxy)-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone  
 N-(4-methoxyphenyl)-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 2-(4-methoxyanilino)-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-1-ethanone dihydrochloride  
 N-(2,4-difluorophenyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 N-(3-chloro-4-methoxyphenyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-1-yl)acetamide  
 2-oxo-N-phenyl-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 N-(2-naphthyl)-2-oxo-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 N-(2,4-difluorophenyl)-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)acetamide  
 8-phenyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-butylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,5-trimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,5-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropyl-2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-pyridinyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-furyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indol-8-yl)benzenethiol  
 8-(2,3-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 8-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-naphthyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 N-[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]acetamide  
 8-(2,3-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-5-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-3-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indole  
 8-[2-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,6-tetrafluorophenyl)-2,34,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-ethoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-isopropoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-ethyl-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 8-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-b  1 H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 8-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 8-(2-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzoate  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-methyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-methyl-3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indol-8-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 [3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[3-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzamide  
 8-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a  
 8-(2,4-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-butylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,5-trimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,5-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-isopropyl-2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-pyridinyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-furyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzenethiol  
 8-(2,3-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4-dimethoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 8-[3-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-naphthyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 N-[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]acetamide  
 8-(2,3-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-5-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(5-fluoro-2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-3-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-ethoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-6-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,4,6-trichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-chloro-2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,6-tetrafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-ethoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[2-chloro-4-isopropoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-ethyl-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 8-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]-2-propen-1-ol  
 8-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluoro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-chloro-4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-benzyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(2-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(4-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 8-(3-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 8-(2-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzoate  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-methyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-methyl-3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzaldehyde  
 [3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanol  
 8-[3-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-8-yl)benzamide  
 7-phenyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-butylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,5-trimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,5-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropyl-2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-pyridinyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-furyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzenethiol  
 7-(2,3-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 7-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-naphthyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 N-[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]acetamide  
 7-(2,3-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-5-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole 7-(2-chloro-3-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole 7-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,6-tetrafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-ethoxyphenyl]-2,3,4,5-tetrahydro-1 H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-isopropoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-ethyl-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 7-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro- 1 H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 7-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 7-(2-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzoate  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-methyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-methyl-3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 [3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[3-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzamide  
 7-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-butylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,5-trimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,5-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-isopropyl-2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-pyridinyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-furyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzenethiol  
 7-(2,3-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4-dimethoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 7-[3-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-naphthyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 N-[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]acetamide  
 7-(2,3-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-5-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(5-fluoro-2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-3-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-ethoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-6-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,4,6-trichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-chloro-2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,6-tetrafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-ethoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[2-chloro-4-isopropoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-ethyl-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 7-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1-H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]-2-propen-1-ol  
 7-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluoro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-chloro-4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-benzyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(2-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(4-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 7-(3-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 7-(2-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzoate  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-methyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-methyl-3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzaldehyde  
 [3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanol  
 7-[3-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-7-yl)benzamide  
 9-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-butylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,5-trimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,5-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropyl-2-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2;6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indole  
 9-[2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-pyridinyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-furyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzenethiol  
 9-(2,3-dichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 9-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-naphthyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 N-[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]acetamide  
 9-(2,3-dimethylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-5-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-nitrophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-3-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethoxy-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluoro-2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methylphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(methylsulfanyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trichlorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-L[1,4]diazepino[1,7-a]indole  
 9-(2,3,4-trifluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2,6-difluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,6-tetrafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-ethoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-isopropoxyphenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-ethyl-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 9-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]in ol-9-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 9-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-4-methoxyphenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-fluorophenyl)-2,3,4,5-tetrahydro-1H-[[1,4]diazepino[1,7-a]indole  
 9-benzyl-2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indole  
 9-(2-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorobenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 9-(2-methoxybenzyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzoate  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-methyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-methyl-3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indol-9-yl)benzaldehyde  
 [3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino [1,7-a]indol-9-yl)phenyl]methanol  
 9-[3-(methoxymethyl)phenyl]-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-fluoro-5-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzamide  
 9-phenyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-butylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,5-trimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,5-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-isopropyl-2-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-pyridinyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-furyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzenethiol  
 9-(2,3-dichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4-dimethoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole 4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 9-[3-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-naphthyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole 1-[4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 N-[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]acetamide  
 9-(2,3-dimethylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-5-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(5-fluoro-2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-chloro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-nitrophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-3-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-ethoxy-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluoro-2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-6-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-(difluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(6-fluoro-2,4-dimethoxylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-methylphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[6-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(methylsulfanyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,4,6-trichlorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,6-dichloro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4-trifluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-chloro-2,6-difluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,6-tetrafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2,3,4,5,6-pentafluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2,6-di(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-ethoxy-2-(trifluoromethoxy)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-isopropoxy-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-chloro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-fluoro-2-(trifluoromethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-ethoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[2-chloro-4-isopropoxyphenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-ethyl-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 9-[4-methoxy-2-(1-hydroxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-[4-methoxy-2-(1-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11 a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]ethanone  
 [5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[4-methoxy-2-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanol  
 1-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-1-propanone  
 methyl (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 methyl 3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]propanoate  
 (2Z)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 methyl (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propenoate  
 (2E)-3-[5-methoxy-2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]-2-propen-1-ol  
 9-[4-methoxy-2-(2-methoxyethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluoro-4-methoxyphenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-chloro-4-fluorophenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-benzyl-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(2-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(4-fluorobenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 9-(3-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 9-(2-methoxybenzyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-ylmethyl)phenol  
 methyl 2-methoxy-6-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzoate  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-methyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile 2-methyl-3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 2-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-trifluoromethyl-4-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile  
 3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzaldehyde  
 [3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanol  
 9-[3-(methoxymethyl)phenyl]-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole  
 N,N-dimethyl[3-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)phenyl]methanamine  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzonitrile, and  
 2-fluoro-5-(2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indol-9-yl)benzamide.  
 
     
     
         8 . A method for treating a disease or disorder of the central nervous system in a mammal comprising administering to said mammal a pharmaceutically effective amount of  
       A compound of formula I:  
       
         
           
           
               
               
           
         
       
       where a is a single bond or double bond, and where 
 R1a, R1b, R2a and R2b are each independently 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6;  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, R7; or  
 (c) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where  
 
 R3 is 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) n N(R6)C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 and Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (b) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where  
 
 R4, R5 and R6 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11 or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or  
 (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; and where  
 
 R7, R8, and R9 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where  
 
 R10, R11 and R12 are each independently H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl;  
 or a stereoisomer or pharmaceutically acceptable salt thereof.  
 
     
     
         9 . The method of  claim 8  wherein the mammal is a human, food animal, companion animal or other type of animal.  
     
     
         10 . The method of  claim 9  wherein the mammal is a human.  
     
     
         11 . The method of  claim 8  wherein said disease or disorder is selected from the group consisting of obesity, depression, schizophrenia, a stress related disease, panic disorder, a phobia, obsessive compulsive disorder, post-traumatic-stress syndrome, immune system depression, incontinence, a stress induced problem with the urinary, gastrointestinal or cardiovascular system, neurodegenerative disorders, autism, chemotherapy-induced vomiting, hypertension, migraine headaches, cluster headaches, sexual dysfunction in a mammal, addictive disorder and withdrawal syndrome, an adjustment disorder, an age-associated learning and mental disorder, anorexia nervosa, apathy, an attention-deficit disorder due to general medical conditions, attention-deficit hyperactivity disorder, bipolar disorder, bulimia nervosa, chronic fatigue syndrome, conduct disorder, cyclothymic disorder, dysthymic disorder, fibromyalgia and other somatoform disorders, generalized anxiety disorder, an inhalation disorder, an intoxication disorder, a movement disorder, oppositional defiant disorder, a pain disorder, peripheral neuropathy, post-traumatic stress disorder, premenstrual dysphoric disorder, a psychotic disorder, seasonal affective disorder, a sleep disorder, a specific developmental disorder, and selective serotonin reuptake inhibition (SSRI) “poop out” syndrome and combinations thereof.  
     
     
         12 . The method of  claim 11  wherein said compound is administered rectally, topically, nasally, orally, sublingually, transdermally or parenterally.  
     
     
         13 . The method of  claim 11  wherein said compound is administered in an amount ranging from about 0.1 to about 50 mg/kg of body weight of said mammal per day.  
     
     
         14 . The method of  claim 13  wherein said compound is administered in an amount ranging from about 0.1 to about 10 mg/kg of body weight of said mammal per day.  
     
     
         15 . A method for modulating 5-HT receptor function, comprising contacting the receptor with an effective inhibitory amount of a compound of a compound of formula I:  
       
         
           
           
               
               
           
         
       
       where a is a single bond or double bond, and where 
 R1a, R1b, R2a and R2b are each independently 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6;  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (c) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where  
 
 R3 is 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) n N(R6)C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 and Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (b) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where  
 
 R4, R5 and R6 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or  
 (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; and where  
 
 R7, R8, and R9 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where  
 
 R10, R11 and R12 are each independently H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl;  
 or a stereoisomer or pharmaceutically acceptable salt thereof.  
 
     
     
         16 . The use of a compound of formula I:  
       
         
           
           
               
               
           
         
       
       where a is a single bond or double bond, and where 
 R1a, R1b, R2a and R2b are each independently 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6;  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (c) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where  
 
 R3 is 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) n N(R6)C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 and Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (b) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where  
 
 R4, R5 and R6 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10OR11, SR10, CO2R10, CONR10R11 or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or  
 (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; and where  
 
 R7, R8, and R9 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where  
 
 R10, R11 and R12 are each independently H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl;  
 or a stereoisomer or pharmaceutically acceptable salt thereof.  
 to prepare a medicament for treating or preventing diseases or disorders of the central nervous system.  
 
     
     
         17 . A substance or a compound of formula I:  
       
         
           
           
               
               
           
         
       
       where a is a single bond or double bond, and where 
 R1a, R1b, R2a and R2b are each independently 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, NR6;  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (c) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR7, OR7, NR7R8, SR7, CO2R7, CONR7R8 or NR7COR8; and where  
 
 R3 is 
 (a) H, Cl, Br, I, F, CN, CF 3 , OCF 3 , alkyl, Ar, OR5, SR5, CHO, CONR5R6, COR5, CO2R5, (Y) o (CH2) n XR5, C(O)C(O)XR5, (Y) o (CH 2 ) n C(O)XR5, C(O)(CH2) n XR5, (Y) o (CH2) n N(R6)C(O)R5, (Y) o (CH2) n N(R6)S(O) 2 R5, (Y) o (CH2) n N(R6)C(O)OR5, (Y) o (CH2) n N(R6)C(O)NR5R6 where o=0 or 1, n=0-3, X=CH 2 , S, O, or NR6 and Y=CH 2 , S, O or NR6, where Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; or  
 (b) linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R8, SR10, CO2R10, CONR10R8 or NR10COR8; and where  
 
 R4, R5 and R6 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl; wherein any of these groups other than H may be optionally substituted with one or more of the following: halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10CO2R10, CONR10R11 or NR10COR11; or where R5 and R6 are linked to form a 3 to 8 member ring; or  
 (b) (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, SO 2 NR7R8, NR7R8, CONR7R8, NR7COR8, NR7CONR8R9, CO 2 R7, COR7, or R7; and where  
 
 R7, R8, and R9 are each independently 
 (a) H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl groups, wherein any of these groups other than H may be optionally substituted with halogen, CN, NO 2 , COR10, OR10, NR10R11, SR10, CO2R10, CONR10R11, NR10COR11, NR10CONR11R12, or where R7, R8, or R9 are linked to form a ring; or  
 (b) (CH2) p Ar where p=0-3 and Ar is aryl or heteroaryl optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR10, CF 3 , OCF 3 , SR10, SO 2 R10, SO 2 NR10R11, NR10R11, CONR10R11, NR10COR11, NR10CONR11R12, CO 2 R10, COR10, or R10; and where  
 
 R10, R11 and R12 are each independently H, linear or branched C 1 -C 8  alkyl, linear or branched C 2 -C 8  alkenyl, linear or branched C 2 -C 8  alkynyl, C 3 -C 8  cycloalkyl, C 3 -C 8  cycloalkenyl, or C 3 -C 8  cycloalkynyl;  
 or a stereoisomer or pharmaceutically acceptable salt thereof.  
 for use as a medicament.  
 
     
     
         18 . A compound of the following formula:  
       
         
           
           
               
               
           
         
       
       where R1a, R1b, R2a and R2b are each independently H, Cl, Br, I, F, CN, CF 3 , OCF 3 , C 1 -C 4  alkyl, OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, or NR6; and 
 R5 and R6 are each independently H, linear, branched or cyclic C 1 -C 8  alkyl, alkenyl, or alkynyl groups or (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl, Ar being optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, NR7R8, CONR7R8, COR7, or R7 where R7 and R8 are each independently H, linear, branched or cyclic C 1 -C8 alkyl, alkenyl, or alkynyl groups, or (CH2) p Ph where p=0-3.  
 
     
     
         19 . A compound of the following formula:  
       
         
           
           
               
               
           
         
       
       where R1a, R1b, R2a and R2b are each independently H, Cl, Br, I, F, CN, CF 3 , OCF 3 , C 1 -C 4  alkyl, OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, or NR6; and 
 R5 and R6 are each independently H, linear, branched or cyclic C 1 -C 8  alkyl, alkenyl, or alkynyl groups or (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl, Ar being optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, NR7R8, CONR7R8, COR7, or R7 where R7 and R8 are each independently H, linear, branched or cyclic C 1 -C 8  alkyl, alkenyl, or alkynyl groups, or (CH2) p Ph where p=0-3.  
 
     
     
         20 . A compound of the following formula:  
       
         
           
           
               
               
           
         
       
       where R1a, R1b, R2a and R2b are each independently H, Cl, Br, I, F, CN, CF 3 , OCF 3 , C 1 -C 4  alkyl, OR5, CONR5R6, COR5, CO2R5, Y(CH 2 ) m XR5 or YC(O)(CH 2 ) m XR5, where m=0-3, Y=CH 2 , S, O, or NR6, X=CH 2 , S, O, or NR6, with the proviso that both R1 and R2 cannot be H; and 
 R5 and R6 are each independently H, linear, branched or cyclic C 1 -C 8  alkyl, alkenyl, or alkynyl groups or (CH 2 ) p Ar where p=0-3 and Ar is aryl or heteroaryl, Ar being optionally substituted with one or more of the following: H, halogen, CN, NO 2 , OR7, CF 3 , OCF 3 , SR7, SO 2 R7, NR7R8, CONR7R8, COR7, or R7 where R7 and R8 are each independently H, linear, branched or cyclic C 1 -C 8  alkyl, alkenyl, or alkynyl groups, or (CH2) p Ph where p=0-3.  
 
     
     
         21 . A compound selected from the group consisting of: 
 tert-butyl 1,2,4,5-tetrahydro-3H-[1,4]diazepino[1,7-a]-indole-3-carboxylate;    11-[(E)-2-nitroethyl]-2,3,4,5-tetrahydro-1,4[1,4]diazepino-[1,7-a]indole;    3-(trifluoroacetyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino-[1,7-1]indole; and    2-bromo-1-1[3-trifluoroacetyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[171-a]indole-11-yl]ethanone;    or a pharmaceutically effective salt thereof.    
     
     
         22 . A method for treating a disease or disorder of the central nervous system is a mammal comprising administering to said mammal a pharmaceutically effective amount of the compound of  claim 21 .  
     
     
         23 . The use of a compound of  claim 21  to prepare a medicament for treating or preventing diseases or disorders of the central nervous system.  
     
     
         24 . A substance or compound of  claim 21  for use as a medicament.  
     
     
         25 . A compound of the formula  
       
         
           
           
               
               
           
         
       
     
     
         26 . A compound of the formula  
       
         
           
           
               
               
           
         
       
     
     
         27 . A compound of the formula
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