Human peroxisome proliferator activated receptor gamma

Abstract

The present invention relates to a novel human peroxisome proliferator activated receptor, hPPARγ. hPPARγ differs from the mouse peroxisome proliferator activated receptor γ in the nucleotide sequence and the amino acid sequence. The invention provides isolated, purified, enriched or recombinant nucleic acid encoding hPPARγ polypeptides and vectors containing thereof, cells transformed with such vectors, and methods of screening for agonists and antagonists of hPPARγ polypeptides. The invention also provides isolated, purified, enriched, or recombinant hPPARγ polypeptides, antibodies having specific binding affinity to hPPARγ polypeptides, and hybridomas producing such antibodies.

1 . Isolated, purified, enriched, or recombinant nucleic acid comprising a contiguous nucleic acid sequence encoding hPPARγ polypeptide.  
     
     
         2 - 41 . (Cancelled).